scispace - formally typeset
Search or ask a question
Journal ArticleDOI

Fabrication of biodegradable electrospun poly(L-lactide-co-glycolide) fibers with antimicrobial nanosilver particles.

01 Oct 2008-Journal of Nanoscience and Nanotechnology (J Nanosci Nanotechnol)-Vol. 8, Iss: 10, pp 5066-5070
TL;DR: The antimicroorganization efficacy of Ag nanoparticles along with the biodegradability of the PLGA fibers can be combined in practical medical applications.
Abstract: Biodegradable poly(lactide-co-glycolide) (PLGA) antimicrobial nanofibers containing silver nanoparticles were prepared by electrospinning technique. Characterization of the Ag/PLGA nanofiber mats were determined by using SEM, TEM, WAXD and UV-vis spectrum. The antibacterial efficacy of the composites mats made of silver nanoparticles and PLGA fibers was measured. The antimicroorganization efficacy of Ag nanoparticles along with the biodegradability of the PLGA fibers can be combined in practical medical applications.
Citations
More filters
Journal ArticleDOI
TL;DR: In this article, different results on the fabrication of nanocomposites based on biodegradable polymers for specific field of tissue engineering are presented, and the combination of bioresorbable polymer and nanostructures open new perspectives in the self-assembly of nanomaterials for biomedical applications with tuneable mechanical, thermal and electrical properties.

850 citations


Cites background from "Fabrication of biodegradable electr..."

  • ...in PLGA matrix nanocomposites can be found in the scientific literature [156,157]....

    [...]

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the possible molecular mechanisms underlying the cytotoxic effects of AgNPs and found that AgNs induced reactive oxygen species (ROS) generation and suppression of reduced glutathione (GSH) in human Chang liver cells.

575 citations

Journal ArticleDOI
TL;DR: Current research trends in nanocomposite materials for tissue engineering, including strategies for fabrication of nanocomPOSite scaffolds with highly porous and interconnected pores are presented.

386 citations

Journal ArticleDOI
TL;DR: In this article, a biological method for the synthesis of silver nanoparticles (AgNPs) using Annona squamosa leaf extract and its cytotoxicity against MCF-7 cells are reported.

322 citations


Additional excerpts

  • ...AgNPs have been extensively applied in urgical instruments, wound dressings, bond prostheses and heart alves, electronics, and biosensing [1,2]....

    [...]

Journal ArticleDOI
TL;DR: In this paper, Chenopodium murale leaf extract was used for the biosynthesis of silver nanoparticles and the results indicated that AgNPs-containing leaf extract showed a higher antioxidant and antimicrobial activity compared to C. murale extract alone or silver nitrate.

316 citations


Cites background from "Fabrication of biodegradable electr..."

  • ...AgNPs are used in coating or embedding for medical purposes [70]....

    [...]