Journal ArticleDOI
Fabrication of porous magnetic nanocomposites for bone tissue engineering
Arundhati Bhowmick,Nilkamal Pramanik,Tapas Mitra,Arumugam Gnanamani,Manas Das,Patit Paban Kundu,Patit Paban Kundu +6 more
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TLDR
In this article, the fabrication and characterization of porous magnetic nanocomposites was carried out via the blending of chitosan, polyethylene glycol and nano-hydroxyapatite-Fe3O4.Abstract:
Here, the fabrication and characterization of porous magnetic nanocomposites was carried out via the blending of chitosan, polyethylene glycol and nano-hydroxyapatite–Fe3O4. Scanning electron microscope images revealed a highly interconnected macro- and micro-porous structure. These nanocomposites showed good water uptake abilities and have good antimicrobial properties. The tensile strengths of these nanocomposites were enhanced significantly compared to previously reported results, after the addition of nano-Fe3O4. Moreover, these nanocomposites could be applied for magnetic therapy as this material exhibited superparamagnetic properties. Finally, these nanocomposites were good supports for human osteoblast-like MG-63 cells’ growth, attachment and proliferation and they showed good cytocompatibility. No negative effect on the MG-63 cells was observed, suggesting that these nanocomposites have great potential to be applied for bone regeneration.read more
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Fabrication of microporous bacterial cellulose embedded with magnetite and hydroxyapatite nanocomposite scaffold for bone tissue engineering
TL;DR: In this paper, a nanocomposite scaffold was synthesized for bone tissue engineering using bacterial cellulose (BC) with magnetite (Fe3O4) and hydroxyapatite (HA) nanoparticles through ultrasonic irradiation.
Journal ArticleDOI
Adaptive Materials Based on Iron Oxide Nanoparticles for Bone Regeneration.
TL;DR: This Minireview aims to summarize the relevant progress and describes the following five aspects: magneto-mechanical actuation in the regulation of cells distribution, mechano-transduction membrane receptors activation, and mechanosensitive signaling pathways regulation, and fabrication, characteristics, and in vitro and in-vivo osteogenic effects of magnetic composite bone scaffolds.
Journal ArticleDOI
State-of-the-art review of fabrication, application, and mechanical properties of functionally graded porous nanocomposite materials
TL;DR: In this paper , the impact of nano-reinforcing agents on the elastic properties of functionally graded porous (FGP) nanocomposites was analyzed and classified for different engineering analysis types including buckling, thermal, vibrational, thermoelasticity, static, and dynamic bending.
Journal ArticleDOI
Trigonella foenum graecum seed polysaccharide coupled nano hydroxyapatite-chitosan: A ternary nanocomposite for bone tissue engineering.
TL;DR: Results of the present study indicate that nHA-CH-TFSP could serve as a prospective analogue for bone tissue engineering.
Journal ArticleDOI
Synthesis, characterization and in vitro screening of a nano-hydroxyapatite/chitosan/Euryale ferox nanoensemble – an inimitable approach for bone tissue engineering
TL;DR: The synthesized scaffold incorporating Euryale ferox with nano-hydroxyapatite and chitosan can be envisioned for potential use in reparation of bone defects as part of ongoing research in the field of bone tissue engineering.
References
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Journal ArticleDOI
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
Ajay Kumar Gupta,Mona Gupta +1 more
TL;DR: This review discusses the synthetic chemistry, fluid stabilization and surface modification of superparamagnetic iron oxide nanoparticles, as well as their use for above biomedical applications.
Journal ArticleDOI
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
TL;DR: Hydrogels are an appealing scaffold material because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner.
Journal ArticleDOI
Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
Journal ArticleDOI
Monodisperse MFe2O4 (M = Fe, Co, Mn) Nanoparticles
Shouheng Sun,Hao Zeng,David B. Robinson,Simone Raoux,Philip M. Rice,Shan X. Wang,Guanxiong Li +6 more
TL;DR: As-synthesized iron oxide nanoparticles have a cubic spinel structure as characterized by HRTEM, SAED, and XRD and can be transformed into hydrophilic ones by adding bipolar surfactants, and aqueous nanoparticle dispersion is readily made.
Journal ArticleDOI
Self-organization mechanism in a bone-like hydroxyapatite/collagen nanocomposite synthesized in vitro and its biological reaction in vivo
TL;DR: This HAp/Col composite having similar nanostructure and composition can replace autologous bone grafts and indicated the same biological properties as grafted bone.
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