Fast robust dose calculation on GPU for high-precision 1 H, 4 He, 12 C and 16 O ion therapy: the FRoG platform
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Cites background or methods or result from "Fast robust dose calculation on GPU..."
...The FRoG dose calculation engine adopts a triple Gaussian distribution model for handling lateral dose distribution as a function of the water equivalent depth [24]....
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...In general, the worsening of the agreement in the case of carbon ions is due to the limitations of handling the lateral dose distributions with a simple triple Gaussian approach [24] as well as the assumption that, for biological calculations, lateral variations of the mixed radiation field are not explicitly considered [26]....
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...6% for patient cases (see Supplementary Material Table S1), in line with results presented previously [24] where calculations of SOBPs in homogenous settings using FRoG were within 1....
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...The improved agreement compared to Syngo is due to the employment of a triple Gaussian parameterization in FRoG instead of a double Gaussian model as in Syngo [24] and an improved handling of the RS for proton beams....
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...As described previously [24], physical and biophysical quantities were simulated and scored depth-wise in water....
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