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PatentDOI

Fatty acids and derivatives of antimicrobial agents

Jon J. Kabara
- 21 May 1975 - 
- Vol. 2, Iss: 1, pp 23-28
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TLDR
The structural relationships of 30 straight-chain fatty acids and derivatives and their bactericidal properties were studied and it is indicated that C12 (lauric acid) is the most inhibitory saturated fatty acid against gram-positive organisms.
Abstract
There is provided a food-grade microbicidal or microbiostatic composition containing a food or food-grade material and as the primary microbicide a mono-ester of a polyol and a twelve carbon atom aliphatic fatty acid.

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Antibacterial activity of selected fatty acids and essential oils against six meat spoilage organisms.

TL;DR: The antibacterial activity of selected fatty acids and essential oils was examined against two gram-negative and four gram-positive bacteria involved in meat spoilage and a relationship was found between the inhibitory effect of essential oils and the presence of eugenol and cinnamaldehyde.
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Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids

TL;DR: The data demonstrate for the first time that the antibacterial action of unsaturated fatty acids is mediated by the inhibition of fatty acid synthesis, and also correlated with antibacterial activity.
References
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Journal ArticleDOI

Influence of trace amounts of fatty acids on the growth of microorganisms.

C. Nieman
TL;DR: A better understanding of the inhibitory and and linolenic acids on pneumococci at a concenstimulating effects of fatty acids on the growth of tration may contribute to a clearer bactericidal influence.
Journal ArticleDOI

Feedback Inhibition of Key Glycolytic Enzymes in Liver: Action of Free Fatty Acids

TL;DR: The biological significance of the inhibition of the key glycolytic enzymes is interpreted as a feedback inhibitory mechanism in regulation of fatty acid biosynthesis and may function for rapid adaptation by which the organism can use the fatty acid level as a metabolic directional switch in decreasing glyCOlysis and turning on gluconeogenesis.
Journal ArticleDOI

The effect of lipids and serum albumin on bacterial growth.

TL;DR: The results suggest that long chain fatty acids can affect the growth of different microbial species through different metabolic channels and that, in order to study the mechanism of these metabolic and growth reactions, it is essential to use the fatty acids under conditions where they cannot manifest their toxic properties.
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