Fibroblast growth factors, their receptors and signaling.
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"Fibroblast growth factors, their re..." refers background in this paper
...The humanfgf-3 gene codes for a 239 amino acid protein (Brookes et al. 1989a) with 44% amino acid homology to FGF-2 in the core region (Dickson & Peters 1987)....
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...Regulation of isoform production has been proposed as a post-transcriptional mechanism for control of FGF-8 activity (MacArthuret al. 1995a)....
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331 citations
"Fibroblast growth factors, their re..." refers background in this paper
...FGF-8 was found to be expressed and secreted in response to treatment with androgens in both the human breast cancer cell line MDA-MB-231 and the 168 www.endocrinology.org SC-3 cell lines (Paysonet al.1996).fgf-8 was also identified as a frequently activated gene in tumors from MMTV-infected Wnt-1…...
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331 citations
"Fibroblast growth factors, their re..." refers background in this paper
...Miller et al. (2000) have recently shown that fgf-1 and fgf-2 double knockout mice displayed similar mild phenotypic defects as fgf-2 single knockout mice, suggesting that FGF-1 is not the factor that compensates for a lack of FGF-2....
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329 citations
"Fibroblast growth factors, their re..." refers background in this paper
...Baird et al. (1988) characterized two functional heparin-binding domains in FGF-2 through the use of peptide blocking studies and localized these domains to amino acids 24-68 and 106-115....
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...However, as there are some splice variants that lack the acid box yet exhibit no peculiarities in dimerization, this mechanism may not be absolutely necessary....
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326 citations
"Fibroblast growth factors, their re..." refers background in this paper
...A series of crosslinking studies identified these high affinity sites as proteins between 125 and 160 kDa (Neufeld & Gospodarowicz 1985, 1986, Friesel et al.1986, Moenneret al.1986, Blanquetet al.1989) which could bind both [125I]FGF-1 and [125I]FGF-2....
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