Fibroblast growth factors, their receptors and signaling.
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"Fibroblast growth factors, their re..." refers background in this paper
...Regulation of this second pathway has yet to be determined, as it seems to function independently of receptor phosphorylation, although this pathway appears at least superficially analogous to that of the insulin receptor and the insulin receptor substrate (IRS)-1 (Yenush & White 1997)....
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264 citations
"Fibroblast growth factors, their re..." refers background in this paper
...fgf-2 mRNA has been shown to be expressed in over 94% of human gliomas (Takahashi et al. 1990); however, the FGF-2 protein has not been detected in normal brain by immunohistochemistry (Takahashi et al....
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258 citations
258 citations
Additional excerpts
...1, IIIb 100 60 34 16 4 5 6 4 4 1, IIIc 100 104 0 102 59 55 0 1 21 2, IIIb 100 9 45 15 5 5 81 4 7 2, IIIc 100 64 4 94 25 61 2.5 16 89 3, IIIb 100 1 2 1 1 1 1 1 42 3, IIIc 100 107 1 69 12 9 1 41 96 4 100 113 6 108 7 79 2 76 75 Modified from Ornitz et al. (1996)....
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253 citations
"Fibroblast growth factors, their re..." refers background in this paper
...The ability of FGFRs in a liganded dimer pair to transphosphorylate each other extends to FGFR heterodimers as well as homodimers (Bellotet al. 1991), allowing for additional complexity in FGF signaling....
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