Fibroblast growth factors, their receptors and signaling.
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"Fibroblast growth factors, their re..." refers background in this paper
...By overexpressing a truncated dominant-negative FGFR-1, Wagner et al. (1998) showed that two human pancreatic cell lines, Panc-1 and MIA PaCa-2, are dependent on signaling through FGFR-1 for activation of the MAP kinase cascade, increased proliferation, and, most importantly, increased tumor formation in vivo in response to FGFs....
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93 citations
"Fibroblast growth factors, their re..." refers background in this paper
...In addition, the regulated expression of cell surface HLGAGs could provide a mechanism for the regulated localization of FGFs (Gould et al. 1995)....
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"Fibroblast growth factors, their re..." refers background in this paper
...HLGAGs oligomerize FGFs, which in turn cross-link FGFRs. (Modified from Spivak-Kroizman et al. 1994a.) Figure 5 Simplification of the model of Venkataraman et al. (1999) and Plotnikov et al. (1999) for FGF-FGFR-HLGAG interaction and receptor dimerization....
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