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Patent

Flexible catheter guidewire

TL;DR: In this article, an apparatus for use as a catheter guidewire and a method for making the catheter's catheter tip is described. But the method is not suitable for catheter insertion.
Abstract: An apparatus for use as a catheter guidewire and a method for making a catheter guidewire. The apparatus comprises an elongate non-coiled wire having a proximal portion, a distal tip and a flexible portion located between the proximal portion and the distal tip having axially spaced grooves cut therein. The method for making the guidewire includes burnishing one end of a wire to create a rounded distal tip and cutting a predetermined pattern of axially spaced grooves in a length of wire adjacent to the distal tip to create a flexible portion.
Citations
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Patent
12 Mar 2001
TL;DR: In this article, the authors presented a set of Disposable Load Unit (DLU) configurations for mounting to a robotic arm for performing at least one surgical task, including a cutting assembly, an aortic hole punch assembly, a lasing assembly, coring assembly, or a vascular suturing assembly.
Abstract: Disposable loading units (DLUs) configured for mounting to a robotic arm for performing at least one surgical task are presented. Each DLU includes an attachment platform having at least one connector for engaging at least one connector on a distal end of the robotic arm for connecting the DLU to the robotic arm, a head portion connected to the attachment platform at one end and configured for housing an electro-mechanical actuation assembly therein, and at least one surgical tool member extending from the head portion and operatively associated with the electro-mechanical actuation assembly for controlling the operation and movement of the at least one surgical tool member. The at least one surgical tool member may include a cutting assembly, an aortic hole punch assembly, a lasing assembly, a coring assembly, or a vascular suturing assembly.

1,132 citations

Patent
05 Oct 2005
TL;DR: In this article, a pulsed electric field was used to induce electroporation or electrofusion of percutaneous intravascular vessels to reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease.
Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

751 citations

Patent
TL;DR: In this paper, a new length of tubing between two sections of a patient's existing body organ tubing and at least partly outside of that existing structure is installed for the purpose of providing the patient with a coronary bypass.
Abstract: Methods and apparatus for delivering and installing a new length of tubing between two sections of a patient's existing body organ tubing and at least partly outside of that existing structure. For example, the new length of tubing may be for the purpose of providing the patient with a coronary bypass. The new tubing may be an artificial graft, a natural graft (harvested elsewhere from the patient), or both. The new tubing is delivered to and installed at the operative site primarily by working through the patient's existing tubular body organ structure. This avoids the need for any significant surgery on the patient. The artificial grafts may have shapes other than tubular. Certain procedural and apparatus aspects of the invention have uses other than in connection with grafting in general or tubular grafting in particular.

638 citations

Patent
27 Oct 2005
TL;DR: In this article, an elongate medical device including an inner elongate member, a reinforcing member, and an outer tubular member is described, where the reinforcing member may be a helically wound continuous wire including a first portion having a first cross-sectional profile, a second portion having another crosssectional profile and a transition region located between the first portion and the second portion.
Abstract: An elongate medical device including an inner elongate member, a reinforcing member, and an outer tubular member is described. The reinforcing member may be a helically wound continuous wire including a first portion having a first cross-sectional profile, a second portion having a second cross-sectional profile, and a transition region located between the first portion and the second portion. The first cross-sectional profile may be different from the second cross-sectional profile. In some embodiments, the first cross-sectional profile may be circular or non-circular and the second cross-sectional profile may be circular or non-circular.

510 citations

Patent
23 Sep 1997
TL;DR: A catheter delivered device to close a septal defect, the device comprising a cylindrical shaft of metal or polymeric material with concentric parallel cuts through the wall of the device which create flattened support struts is described in this paper.
Abstract: A catheter delivered device to close a septal defect, the device comprising a cylindrical shaft of metal or polymeric material with concentric parallel cuts through the wall of the device which create flattened support struts. The center of the support struts move radially away from the axis in a hinge like fashion in response to the movement of the device's proximal and distal ends toward the center of the device. This movement is reversibly effected through mechanical means. The device can be coated with growth factors, mitogenic factors or other determinants which can improve tissue growth such that tissue ingrowth can occur over a period of time. The catheter itself may be an ultrasonic imaging catheter.

327 citations

References
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Patent
04 Sep 1992
TL;DR: In this article, a flexible tubular member can be formed by cutting a predetermined configuration of slots into a single hollow thin-walled metal tube at predetermined spacings, depth and patterns.
Abstract: An apparatus for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire. The apparatus (20) including a flexible metallic tubular member (22) with an encasing (26) covering the tubular member that creates a fluid-tight seal around the periphery of the tubular member. In one embodiment, the tubular member can be a coiled metallic hypotube design. This coiled design can include either a single filament or multi-filament wire wrap. In a second embodiment, the flexible tubular member can be formed by cutting a predetermined configuration of slots into a single hollow thin-walled metal tube at predetermined spacings, depth and patterns.

638 citations

Patent
27 Jan 1984
TL;DR: In this article, a guide wire for a catheter having a body portion comparatively high in rigidity and a distal end portion comparatively flexible is presented, where the body portion is made of a super-elastic metallic member.
Abstract: A guide wire for a catheter having a body portion comparatively high in rigidity and a distal end portion comparatively flexible. At least portions of the body portion and the distal end portion are formed of a super-elastic metallic member. At least portions of inner core portions on the body portion's side and on the distal end portion's side, both of which are coated by a plastic, are formed of the super-elastic metallic member, and at least a portion of the inner core portion on the distal end portion's side is made smaller in cross-section than the inner core portion on the body portion's side. In consequence, the catheter can be reliably and readily introduced to a predetermined position.

408 citations

Patent
09 Apr 1991
TL;DR: The Ni-Ti linear elastic alloy was used in the construction of the guidewire (10) as discussed by the authors, which exhibits a stress-strain curve with a linear stressstrain relationship and a yield point, and is deformable beyond the yield point to a desired set shape.
Abstract: A guidewire (10) and a method for its manufacture, wherein at least the distal portion (18) of the guidewire (10) comprises an element made of a precursor of a superelastic alloy such as a Ni-Ti linear elastic alloy. The element exhibits a stress-strain curve with a linear stress-strain relationship and a yield point. At room temperature to body temperature the precursor is in the martensitic phase. The distal portion (18) of the guidewire (10) is deformable beyond the yield point by the physician in the field to a desired set shape and exhibits resistance to kinking during insertion into the body as a result of its elasticity.

404 citations

Patent
27 Apr 1990
TL;DR: A catheter guide wire is for use in guiding of a catheter to a destination position in vessels in body and comprises a solid core wire of a Ti-Ni shape memory alloy and an outer jacket covering the core wire as mentioned in this paper.
Abstract: A catheter guide wire is for use in guiding of a catheter to a destination position in vessels in body and comprises a solid core wire of a Ti-Ni shape memory alloy and an outer jacket covering the core wire. In order to provide a plasticity to one end portion of the core wire, at least one end portion is made of a 45.0-51.0 at % Ni-0.5-5.0 at % Fe-Ti shape memory alloy and is heat treated at 400°-500° C. The end portion is provided with a pseudo elasticity at a temperature about 37° and a plasticity at a temperature below 80° C. Alternatively, the end portion may be made of a 50.3-52.0 at % Ni-Ti alloy and is heat treated at a temperature of 700° C. In order to improve operability of the catheter guide wire, the remaining portion other than the end portion is made of provided with a comparatively high rigidity by a usual Ti-Ni shape memory alloy which is not heat treated. Alternatively, the remaining portion is covered with an inorganic layer. The inorganic layer is a coating and alternatively is a cladding. The solid core wire is covered with a synthetic resin layer to form the catheter guide wire.

229 citations

Patent
12 May 1987
TL;DR: In this paper, a small diameter steerable guidewire for cardiovascular surgical procedures or the like is provided with a means by which the curvature at the distal tip of the guidance can be adjustable by control applied at the proximal end of the guide.
Abstract: A small diameter (no greater than about 0.020" diameter) steerable guidewire for cardiovascular surgical procedures or the like is provided with a means by which the curvature at the distal tip of the guidewire can be adjustable by control applied at the proximal end of the guidewire whereby the curve at the distal end of the guidewire can be adjusted without requiring removal of the guidewire from the patient.

200 citations