Journal ArticleDOI
Fluorescent staining of heteropycnotic chromosome regions in human interphase nuclei.
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,Clas B. Johansson,Clas B. Johansson,Jan Lindsten,Jan Lindsten,Maj Hultén,Maj Hultén +9 more
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This article is published in Experimental Cell Research.The article was published on 1970-08-01. It has received 99 citations till now. The article focuses on the topics: Chromosome regions & Interphase.read more
Citations
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Journal ArticleDOI
The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability.
TL;DR: Apart from certain minor but well defined chromosome regions with especially strong fluorescence, which are subject to certain individual variations, the fluorescence patterns were shown to be quite stable and reproducible.
Journal Article
Analytic review: nature and origin of males with XX sex chromosomes.
TL;DR: A review of the available data may serve to throw some light on a number of problems pertaining to males with the karyotype 46,XX, and it is hoped that by summarizing the present knowledge it will be easier to define more sharply the tasks of future research in the field.
Journal Article
Sex chromatin of donor corneal epithelium in rabbits.
TL;DR: Investigation in rabbits after they received unilateral 8 mm diameter lamellar keratoplasties with living donor tissue of a different sex from the host indicated that some of the donor corneal epithelium survived up to 12 weeks postoperatively, even in the absence of overt epithelial rejection.
Journal ArticleDOI
Cytogenetic identification of allogeneic epidermal Langerhans cells in a bone-marrow-graft recipient.
Book ChapterDOI
Linkage analysis using somatic cell hybrids
TL;DR: This article shall focus on the utilization of somatic cell populations for the purpose of establishing the linkage relationships of genes to other genes and genes to chromosomes in higher eukaryotic organisms—especially man.
References
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Journal ArticleDOI
Identification of human chromosomes by DNA-binding fluorescent agents
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,Clas B. Johansson,Clas B. Johansson,E.J. Modest,E.J. Modest +7 more
TL;DR: A convenient measuring technique has been developed for the rapid and accurate recording of fluorescence patterns in human metaphase chromosomes that should be particularly valuable for the identification of chromosomes 4–5 and the individual types in the 6–12 group.
Journal ArticleDOI
Differential binding of alkylating fluorochromes in human chromosomes.
TL;DR: Human metaphase chromosomes from blood cultures, treated with quinacrine mustard, show a banded pattern of fluorescence, which in the chromosomes with the most strongly fluorescent regions (3, 13–15 and Y) was found to be constant and reproducible.
Journal ArticleDOI
Chemical differentiation along metaphase chromosomes.
Torbjörn Caspersson,Torbjörn Caspersson,S. Farber,S. Farber,G.E. Foley,G.E. Foley,J. Kudynowski,J. Kudynowski,E.J. Modest,E.J. Modest,E. Simonsson,E. Simonsson,U. Wagh,U. Wagh,Lore Zech,Lore Zech +15 more
Journal ArticleDOI
Technique for Identifying Y Chromosomes in Human Interphase Nuclei
TL;DR: This work investigated the possibility of positively identifying male nuclei in interphase by virtue of this staining property of the Y chromosome using quinacrine dihydro-chloride.
Journal ArticleDOI
Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes.
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,E.J. Modest,E.J. Modest,G.E. Foley,G.E. Foley,U. Wagh,U. Wagh,E. Simonsson,E. Simonsson +11 more
TL;DR: A bifunctional highly fluorescent quinacrine mustard was shown to give chromosome breaks preferentially localized to heterochromatic chromosome regions (identifiable by cold treatment) in the M-chromosome.