Journal ArticleDOI
Formulation of self-emulsifying drug delivery systems
Reads0
Chats0
TLDR
Self-emulsifying drug delivery systems (SEDDS) are mixtures of oils and surfactants, ideally isotropic, sometimes including cosolvents, which emulsify under conditions of gentle agitation, similar to those which would be encountered in the gastro-intestinal tract as discussed by the authors.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 1997-04-14. It has received 600 citations till now. The article focuses on the topics: Dosage form.read more
Citations
More filters
Journal ArticleDOI
Microemulsion-based media as novel drug delivery systems
M. Jayne Lawrence,Gareth D. Rees +1 more
TL;DR: The use of microemulsions and closely related microemulsion-based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future directions.
Journal ArticleDOI
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs.
R. Neslihan Gürsoy,Simon Benita +1 more
TL;DR: Self-emulsifying drug delivery systems (SEDDS), which are isotropic mixtures of oils, surfactants, solvents and co-solvents/surfactants, can be used for the design of formulations in order to improve the oral absorption of highly lipophilic drug compounds as discussed by the authors.
Journal ArticleDOI
Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems.
TL;DR: A simple classification system for lipid formulations, based on the polarity of the blend and reviewed here, will help comparison of data between laboratories and priorities for future work are discussed.
Journal ArticleDOI
Design and Production of Nanoparticles Formulated From Nano-Emulsion Templates-A Review
TL;DR: A link between nano-emulsion formulation methods and nanoparticle generation is proposed, while at the same time bearing in mind the above-mentioned parameters for active molecule encapsulation.
Journal ArticleDOI
Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies.
TL;DR: The properties of excipients are discussed, the formulation strategies that can be used for each type of lipid formulation are outlined, and a framework for the in vitro testing of each type is suggested.
References
More filters
Book
Encyclopedia of Pharmaceutical Technology
TL;DR: Compounding, Contemporary, andProcess Chemistry in the Pharmaceutical Industry: Characterization and Function, Volume 19.
Journal ArticleDOI
Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects
TL;DR: This review highlights the state-of-the-art in pharmaceutical microemulsions with emphasis on self-emulsifying systems, from both a physical and biopharmaceutical perspective, primarily focused on their potential for oral drug delivery and intestinal absorption improvement.
Book
Colloidal Drug Delivery Systems
TL;DR: Ointments and creams as colloidal drug delivery systems microemulsions liposomes niosomes nanoparticles niosome nanoparticles.
Book
Surfactant Systems: Their chemistry, pharmacy and biology
TL;DR: In this paper, the phase behavior of surfactants in binary and ternary phase systems is investigated. But the authors focus on the phase behaviour of the solubilization process.
Journal ArticleDOI
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
TL;DR: This review attempts to provide a framework for the assessment of lipid based formulations by describing how aspects of GI physiology, and the choice of lipids and their formulation attributes, impact on dose form performance.
Related Papers (5)
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs.
R. Neslihan Gürsoy,Simon Benita +1 more