Four phenolic neolignans from Magnolia liliflora
TL;DR: A chloroform extract of fresh leaves of Magnolia liliflora contained the four new phenolic neolignans, liliflodione [a bicyclo(3,2,1) octanoid], liliflol A and B (dihydrobenzofuranoids) and liliflanone (a hexahydron-hexahedronoid) as mentioned in this paper.
About: This article is published in Phytochemistry.The article was published on 1983-01-01. It has received 32 citations till now.
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TL;DR: The results obtained in this study support the role of essential oil and the leaf extracts derived from M. liliflora as a remarkable approach to inhibit the growth of food spoilage and foodborne pathogens.
Abstract: The aim of this study was to examine the chemical composition of the essential oil isolated from the floral parts of Magnolia liliflora Desr. by hydrodistillation, and to test the efficacy of essential oil and various leaf extracts against a diverse range of microorganisms comprising food spoilage and foodborne pathogenic bacteria. The chemical composition of essential oil was analyzed by GC-MS. It was determined that 52 compounds, which represented 78.07% of total oil, were present in the oil. The oil contained mainly levoxine (15.59%), methylcyclopropane (24.26%), 2-beta-pinene (5.3%), caryophyllene oxide (4.01%), and beta-caryophyllene (1.7%). The oil (1000 ppm/disc) and leaf extracts (1500 ppm/disc) exhibited promising antibacterial effects against the tested pathogens as a diameter of zones of inhibition (9 to 18 and 7 to 12 mm) and MIC values (125 to 1000 and 500 to 3000 microg/mL), respectively. Also, the oil had a potent detrimental effect on the viable count of the tested bacteria. The results obtained in this study support the role of essential oil and the leaf extracts derived from M. liliflora as a remarkable approach to inhibit the growth of food spoilage and foodborne pathogens.
84 citations
Cites background from "Four phenolic neolignans from Magno..."
...liliflora leaf and twig have been reported previously (Talapatra and others 1982; Iida and Ito 1983)....
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...liliflora as observed earlier by others (Talapatra and others 1982; Iida and Ito 1983)....
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TL;DR: Three new rearranged prenylated C(6)-C(3) compounds, named illioliganones A, B, and C (1-3), and a new highly oxygenated seco-prezizaane-type sesquiterpene, oligandriortholactone (7), together with three known prenylon compounds (4-6), have been isolated from the stem bark of Illicium oligandrum.
Abstract: Three new rearranged prenylated C 6 -C 3 compounds, named illioliganones A, B, and C (1-3), and a new highly oxygenated seco-prezizaane-type sesquiterpene, oligandriortholactone (7), together with three known prenylated C 6 -C 3 compounds (4-6) and a known sesquiterpene lactone (8), have been isolated from the stem bark of Illicium oligandrum. The structures of 1-3 and 7 were elucidated by spectroscopic methods including 1D and 2D NMR, HRMS, and CD experiments. The absolute configuration of the 11,12-diol moiety in 2 and 3 was determined on the basis of observing the induced circular dichroism after addition of Mo 2 (OAc) 4 in DMSO solution. The anti-inflammatory and cytotoxic activities of 1-8 were evaluated.
50 citations
TL;DR: Kadsurenone, a specific receptor antagonist of platelet-activating factor and a natural product isolated from Piper futokadsura, was prepared in three steps from 3,4-dimethoxycinnamyl alcohol and allyloxyphenol via rac -(2S,3S)-5-allyl-6-hydroxy-2-(3, 4-dimethyl-henyl)-3-methyl-2,3-dihydrobenzofuran as discussed by the authors.
33 citations
TL;DR: In this article, an efficient cycloaddition of ortho-hydroxyphenylsubstituted para-quinone methides and sulfur ylides was achieved under the catalyst-free condition.
30 citations
TL;DR: An enantio- and diastereoselective organocatalytic domino Michael/Aldol reaction for the direct preparation of synthetically and medicinally relevant bicyclo[3.2.1]octane derivatives with four stereogenic centers, including two quaternary carbons, has been described.
28 citations
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TL;DR: Two new biphenyl ether lignans were isolated from the leaves of Magnolia obovata THUNB and showed antibacterial activity against a cariogenic bacterium, Streptococcus mutans, but was less active than magnolol (5) and honokiol (6).
Abstract: Two new biphenyl ether lignans, named obovatol (1) and obovatal (2) were isolated from the leaves of Magnolia obovata THUNB. (Magnoliaceae) and their chemical structures were determined to be 4', 5-diallyl-2, 3-dihydroxybiphenyl ether and 3, 4-dihydroxy-5-(pallylphenoxy) cinnamic aldehyde by means of chemical and spectral studies. The former substance showed antibacterial activity against a cariogenic bacterium, Streptococcus mutans, but was less active than magnolol (5) and honokiol (6).
81 citations
TL;DR: Two new hydroperoxysesquiterpenes, k Kobusimin A and B, have been isolated from the leaves of Magnolia kobus.
68 citations
TL;DR: New neolignans, denudatin A and B (hydrobenzofuranoids) and denudatone [spiro(5,5)undecanoid], together with three known NELLANS including burchelli are described in this paper.
33 citations
TL;DR: In this paper, seven neolignans, isolated from a C 6 H 6 extract of Nectandra miranda (Lauraceae) trunk wood, included the hitherto undescribed (2 S, 3 S, 3a S )- and (2 R, 3 R )-7-methoxy-2-(3′, 4′, 5′-trimethoxyphenyl)-3-methylbenzofuran (licarin C).
25 citations
TL;DR: This is the first report of two neolignans of spirocyclohexadienone skeleton and of taspine from the Magnoliaceae family and the second report of the natural occurrence of futoenone.
22 citations