Frailty status at admission to hospital predicts multiple adverse outcomes.
Ruth E. Hubbard,Nancye M. Peel,Mayukh Samanta,Leonard C. Gray,Arnold Mitnitski,Kenneth Rockwood +5 more
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The interRAI-AC can be used to derive a single score that predicts multiple adverse outcomes in older inpatients, and a score of ≤0.40 can well discriminate patients who are unlikely to die or experience a geriatric syndrome.Abstract:
Aims: frailty is proposed as a summative measure of health status and marker of individual vulnerability We aimed to investigate the discriminative capacity of a frailty index (FI) derived from interRAI Comprehensive Geriatric Assessment for Acute Care (AC) in relation to multiple adverse inpatient outcomesread more
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Development and validation of a hospital frailty risk score focusing on older people in acute care settings using electronic hospital records; an observational study
Thomas Gilbert,Jenny Neuburger,Joshua Kraindler,Eilís Keeble,Paul V. Smith,Cono Ariti,Sandeepa Arora,Andrew Street,Stuart G Parker,Helen C. Roberts,Martin Bardsley,Simon Conroy +11 more
TL;DR: The Hospital Frailty Risk Score provides hospitals and health systems with a low-cost, systematic way to screen for frailty and identify a group of patients who are at greater risk of adverse outcomes and for whom a frailty-attuned approach might be useful.
Journal ArticleDOI
Frailty and Delirium in Older Adults: A Systematic Review and Meta‐Analysis of the Literature
Ilaria Persico,Matteo Cesari,Matteo Cesari,Alessandro Morandi,Justin Haas,Paolo Mazzola,Antonella Zambon,Giorgio Annoni,Giuseppe Bellelli +8 more
TL;DR: To evaluate the relationship between frailty and delirium, researchers used a probabilistic method to estimate the likelihood of serious adverse events such as strokes, heart attacks, and strokes in patients with a history of frailty.
Journal ArticleDOI
Frailty as a predictor of adverse outcomes in hospitalized older adults: A systematic review and meta-analysis.
TL;DR: Being frail at hospital admission is a risk factor for in-hospital mortality, long hospital stay, functional decline at hospital discharge, and mortality in the medium- and long-term.
Journal ArticleDOI
Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records.
R.K. Owen,Simon Conroy,Nick Taub,Will Jones,Daniele Bryden,Manish Pareek,Christina Faull,Keith R. Abrams,Daniel Davis,Jay Banerjee +9 more
TL;DR: In this paper, the authors describe outcomes in hospitalised older people with different levels of frailty and COVID-19 infection, and find that frailty appeared to make little incremental contribution to the hazard of dying in older people hospitalised with COVID19 infection; illness severity and comorbidity had a modest association with the overall adjusted hazard of death.
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Differences in frailty in older men and women.
Emily H Gordon,Ruth E. Hubbard +1 more
TL;DR: Sex differences in the effectiveness of frailty interventions have not been addressed in the research literature to date, and successful interventions may target many (if not all) biopsychosocial domains, with careful consideration of issues relevant to each sex.
References
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Book
Applied Logistic Regression
David W. Hosmer,Stanley Lemeshow +1 more
TL;DR: Hosmer and Lemeshow as discussed by the authors provide an accessible introduction to the logistic regression model while incorporating advances of the last decade, including a variety of software packages for the analysis of data sets.
Journal ArticleDOI
Applied Logistic Regression.
TL;DR: Applied Logistic Regression, Third Edition provides an easily accessible introduction to the logistic regression model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables.
Journal ArticleDOI
Frailty in elderly people
TL;DR: Developing more efficient methods to detect frailty and measure its severity in routine clinical practice would greatly inform the appropriate selection of elderly people for invasive procedures or drug treatments and would be the basis for a shift in the care of frail elderly people towards more appropriate goal-directed care.
Journal ArticleDOI
A global clinical measure of fitness and frailty in elderly people
Kenneth Rockwood,Xiaowei Song,Chris MacKnight,Howard Bergman,David B. Hogan,Ian McDowell,Arnold Mitnitski +6 more
TL;DR: The ability of the Clinical Frailty Scale to predict death or need for institutional care, and correlated the results with those obtained from other established tools are determined.