Journal ArticleDOI
Functionalized biomaterials to combat biofilms
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TLDR
It is believed that all of these strategies, alone or in combination, could represent a blueprint for fighting biofilm-associated infections in the postantibiotic era.Abstract:
Pathogenic microbial biofilms that readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies towards biofilms, leaving a thought-provoking question: how to tackle the problem of established biofilms? In this review, we briefly summarize the functionalized biomaterials to combat biofilms and highlight current approaches to eradicate pre-existing biofilms. We believe that all of these strategies, alone or in combination, could represent a blueprint for fighting biofilm-associated infections in the postantibiotic era.read more
Citations
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Dual-function antibacterial surfaces to resist and kill bacteria: Painting a picture with two brushes simultaneously
TL;DR: In this article, the authors summarized the recent development of these dual-function antibacterial surfaces and highlighted the representative examples, which are categorized specifically into two types according to the anti-adhesive and bactericidal properties are simultaneous or switchable.
Journal ArticleDOI
Therapeutic strategies against bacterial biofilms
Yufang Bi,Guixue Xia,Chao Shi,Jianglin Wan,Longqiang Liu,Yuan Chen,Yueming Wu,Wenjing Zhang,Min Zhou,Hongyan He,Runhui Liu +10 more
TL;DR: The current strategies to eliminate mature biofilms and progress in related drug delivery nanosystems are reviewed, with the aim of inspiring researchers to design new antibiofilm systems.
Journal ArticleDOI
Universal Antifouling and Photothermal Antibacterial Surfaces Based on Multifunctional Metal-Phenolic Networks for Prevention of Biofilm Formation.
Yaran Wang,Yi Zou,Yong Wu,Ting Wei,Kunyan Lu,Luohuizi Li,Yuancheng Lin,Yan Wu,Chaobo Huang,Yanxia Zhang,Hong Chen,Qian Yu +11 more
TL;DR: Wang et al. as mentioned in this paper developed a facile method for endowing diverse substrates with long-term antibiofilm property by deposition of a hybrid film composed of tannic acid/Cu ion (TA/Cu) complex and poly(ethylene glycol) (PEG).
Journal ArticleDOI
Sprayable antibacterial Persian gum-silver nanoparticle dressing for wound healing acceleration
Armin Amirsadeghi,Armin Amirsadeghi,Arman Jafari,Seyyedeh-Sara Hashemi,Aboozar Kazemi,Younes Ghasemi,Amin Derakhshanfar,Mohammad-Ali Shahbazi,Mohammad-Ali Shahbazi,Seyyed Vahid Niknezhad +9 more
TL;DR: Cytotoxicity and in vivo full-thickness wound healing evaluation confirmed that 1% PG/Ag-NPs spray was safe and improved wound healing process, and confirmed the high potential of formulated sprayable dressings for wound repair.
Journal ArticleDOI
Photocatalytic graphitic carbon nitride-chitosan composites for pathogenic biofilm control under visible light irradiation.
Hongchen Shen,David P. Durkin,Ashlee Aiello,Tara Diba,John Lafleur,Jason M. Zara,Yun Shen,Danmeng Shuai +7 more
TL;DR: Visible-light-responsive composites of carbon-doped graphitic carbon nitride and chitosan with high reactivity and processability were fabricated, and they can control pathogenic biofilms for environmental, food, biomedical, and building applications.
References
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Journal ArticleDOI
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Hans-Curt Flemming,Jost Wingender,Ulrich Szewzyk,Peter D. Steinberg,Scott A. Rice,Staffan Kjelleberg +5 more
TL;DR: The fundamental role of the biofilm matrix is considered, describing how the characteristic features of biofilms — such as social cooperation, resource capture and enhanced survival of exposure to antimicrobials — all rely on the structural and functional properties of the matrix.
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Bioinspired self-repairing slippery surfaces with pressure-stable omniphobicity
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TL;DR: A strategy to create self-healing, slippery liquid-infused porous surface(s) (SLIPS) with exceptional liquid- and ice-repellency, pressure stability and enhanced optical transparency, applicable to various inexpensive, low-surface-energy structured materials (such as porous Teflon membrane).
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Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
TL;DR: A historic perspective on the development of the field is provided, common trends are emphasized, and new directions in c-di-GMP research are highlighted that will give a deeper understanding of this truly universal bacterial second messenger.
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Implant infections: adhesion, biofilm formation and immune evasion
TL;DR: The fundamental pathogenic mechanisms underlying implant infections are explored, highlighting orthopaedic implants and Staphylococcus aureus as a prime example, and innovative targets for preventive and therapeutic strategies are discussed.
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Targeting microbial biofilms: current and prospective therapeutic strategies.
TL;DR: This Review focuses on current therapeutic strategies and those under development that target vital structural and functional traits of microbial biofilms and drug tolerance mechanisms, including the extracellular matrix and dormant cells.
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