Journal ArticleDOI
Gastric Microbiota
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TLDR
In this article, a non-H.pylori microbial community has been recently observed in the human stomach, the so-called human gastric microbiota, along with H. pylori itself.Abstract:
After the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture-independent methods of analysis, a non-H. pylori microbial community has been recently observed in the human stomach, the so-called human gastric microbiota, along with H. pylori itself. Increasing evidence supports the hypothesis that although H. pylori may be the most relevant, it is not the only local bacterial culprit leading to gastric diseases. Further studies are warranted to offer a better picture of the role and functions of gastric microbiota and to identify the best therapeutic modulators of gut microbiota for the management of gastric diseases.read more
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Journal ArticleDOI
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
Peter Malfertheiner,Francis Mégraud,Colm O'Morain,Javier P. Gisbert,Ernst J. Kuipers,A. T. R. Axon,Franco Bazzoli,Antonio Gasbarrini,John Atherton,David Y. Graham,Richard H. Hunt,Paul Moayyedi,Theodore Rokkas,Massimo Rugge,Michael Selgrad,Sebastian Suerbaum,Kentaro Sugano,Emad M. El-Omar +17 more
TL;DR: This fifth edition of the Maastricht Consensus Report describes how experts from 24 countries examined new data related to H. pylori infection in the various clinical scenarios and provided recommendations on the basis of the best available evidence and relevance.
Journal ArticleDOI
Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan.
Yung-Yu Hsieh,Yung-Yu Hsieh,Shui-Yi Tung,Shui-Yi Tung,Hung-Yu Pan,Chih-Wei Yen,Chih-Wei Yen,Huang-Wei Xu,Huang-Wei Xu,Ying-Jhen Lin,Yi-Fang Deng,Wan-Ting Hsu,Cheng-Shyong Wu,Cheng-Shyong Wu,Chin Li +14 more
TL;DR: The findings indicate that the gastric microenvironment is frequently colonised by Clostridium and Fusobacterium in patients with gastric cancer.
Journal ArticleDOI
The interaction between smoking, alcohol and the gut microbiome.
Gabriele Capurso,Edith Lahner +1 more
TL;DR: The exact cause-effect relation between alcohol and smoking and changes of the gastrointestinal microbiome needs further exploration with high throughput methodologies, and controlled studies are necessary to define the role of microbiome modulation on the immune response and systemic activation of pro-inflammatory pathways.
Journal ArticleDOI
Microbiota at the crossroads of autoimmunity
TL;DR: It is suggested that many of the known cues affecting the function of the immune system, such as genetics, gender, pregnancy and diet, exert their effects by influencing, at least in part, the microbiota composition and activity, which modulates the immune response in a way that increases the risk for autoimmunity in predisposed individuals.
Journal ArticleDOI
Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer.
Jose B. Saenz,Jason C. Mills +1 more
TL;DR: It is proposed that the stomach, like other organs, exhibits marked cellular plasticity: the glandular response involves reprogramming mature cells to serve as auxiliary stem cells that replace lost cells.
References
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Journal ArticleDOI
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Journal ArticleDOI
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Journal ArticleDOI
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Journal ArticleDOI
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Journal ArticleDOI
Inflammation and intestinal metaplasia of the distal esophagus are associated with alterations in the microbiome
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