Gender differences in the association of visceral and subcutaneous adiposity with adiponectin in African Americans: the Jackson Heart Study
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Cites background from "Gender differences in the associati..."
...The protective action of gluteal femoral SQF seems to be further limited to the femoral subcutaneous region and not necessarily with the gluteal region in black South African women further confounding the issue with ethnicity differences.(11,16,25,27,29-32) Indeed, even gender appears to have a profound influence on the responses by different adipose depots....
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...Indeed, even gender appears to have a profound influence on the responses by different adipose depots.(16,32-34) One mechanism that seems universal in human adipose depot regulation of adipose tissue is insulin, although, with as much variation within one species (human) one can only imagine the differences which exist between species....
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...Issues associated with adipose depot include disruption of normal function of organs due to infiltration with lipid-filled adipocytes—for example, nonalcoholic fatty livers are not capable of functioning as properly as normal livers, and is likely a precursor of fatty infiltration into other organs/tissues.(9,16) An interest of this paper is on the specific differences in INTMF vs....
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61 citations
Cites background from "Gender differences in the associati..."
...They secrete in large amounts TNF-α, IL-6, IL-12, IL-1β, and monocyte chemotactic protein-1 (MCP-1), as well as nitric oxide (NO) (24)....
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...Adiponectin exerts anti-inflammatory activities, inhibiting IL-6 and TNF-α production (112)....
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...On the other hand, IL-1β, IL-6, and IL-8 serum levels were increased in asthmatic obese and obese children in comparison to asthmatic children and controls....
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...Treated subjects exhibited a significant reduction in weight as well as in TNF-α and IL-6 with an increase in adiponectin in comparison to the placebo group....
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...In view of its beneficial activities, melatonin has successfully been used in rats with MetS diminishing insulin resistance, release of TNF-α and IL-6 from adipocytes, low-density lipoprotein, and very low-density lipoprotein plasma levels and body weight (182)....
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60 citations
Cites background from "Gender differences in the associati..."
...The majority of studies also support that ADP levels are inversely associated with obesity, with obese individuals having lower fasting ADP levels.(36,37) In the first trial evaluating interictal ADP levels in episodic and chronic migraineurs,(38) ADP and its multimers were measured in 37 participants (EM: 13; CM: 12; Control 12)....
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54 citations
References
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12,394 citations
"Gender differences in the associati..." refers background in this paper
..., leptin [42], adiponectin [43], tumor necrosis factor-α (TNF-α) [44], plasminogenactivator inhibitor type-1 (PAI-1) [45] and resistin [46]....
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7,347 citations
Additional excerpts
...Several studies have demonstrated that adipose tissue actively produces a variety of locally and systemically functioning bioactive molecules that interact in various obesity-related diseases, e.g., leptin [42], adiponectin [43], tumor necrosis factor-α (TNF-α) [44], plasminogenactivator inhibitor type-1 (PAI-1) [45] and resistin [46]....
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..., leptin [42], adiponectin [43], tumor necrosis factor-α (TNF-α) [44], plasminogen-activator inhibitor type-1 (PAI-1) [45] and resistin [46]....
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4,882 citations
4,557 citations
Additional excerpts
..., leptin [42], adiponectin [43], tumor necrosis factor-α (TNF-α) [44], plasminogen-activator inhibitor type-1 (PAI-1) [45] and resistin [46]....
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