Journal ArticleDOI
Gender-related disparities in non-small cell lung cancer
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TLDR
Gender differences in terms of risk factors, histopathological features and pathogenetic mechanisms in NSCLC are summarized, and it is hypothesized that a gender-oriented pharmacology could beneficially impact on innovative therapeutic strategies.Citations
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Lung Cancer in Never Smokers - Different Disease
TL;DR: Current knowledge of lung cancers arising in never smokers versus smokers is summarized, suggesting that they are separate entities.
Journal ArticleDOI
Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival
Juliana Navarro-Yepes,Juliana Navarro-Yepes,Michaela Burns,Annadurai Anandhan,Oleh Khalimonchuk,Luz M. Del Razo,Betzabet Quintanilla-Vega,Aglaia Pappa,Mihalis I. Panayiotidis,Rodrigo Franco +9 more
TL;DR: This review will focus on the molecular mechanism by which ROS/RNS generation, redox signaling, and/or oxidative stress/damage alter autophagic flux rates, and the role of autophagy as a cell death process or survival mechanism in response to oxidative stress.
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Nutrition and human health from a sex–gender perspective
TL;DR: This article will review some of the differences underlying the impact of food components on the risk of developing diseases from a sex-gender perspective.
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Redox signaling: Potential arbitrator of autophagy and apoptosis in therapeutic response
TL;DR: This review will focus on understanding the delicate molecular mechanism by which autophagy and apoptosis are finely orchestrated by redox signaling and discuss how this understanding can be used to develop strategies for the treatment of cancer.
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A Machine-Learning Approach Using PET-Based Radiomics to Predict the Histological Subtypes of Lung Cancer.
TL;DR: A machine-learning approach successfully identified the histological subtypes of lung cancer and a PET-based radiomic features may help clinicians improve the histopathologic diagnosis in a noninvasive manner.
References
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Journal ArticleDOI
Cancer Statistics, 2009
TL;DR: The most recent data on cancer incidence, mortality, and survival from the American Cancer Society (ACS) is presented in this paper, where the authors compare the three major cancer sites in men (lung, prostate, and colon and rectum [colorectum]) and in two major cancers sites in women (breast and colorectal) over a 15-year period.
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Papillomaviruses and cancer: from basic studies to clinical application
TL;DR: Links between human papillomaviruses (HPVs) and cervical cancer were first suspected almost 30 years ago and DNA of specific HPV types has since been found in almost all cervical cancer biopsies.
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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
Guido Kroemer,Guido Kroemer,Guido Kroemer,Lorenzo Galluzzi,Lorenzo Galluzzi,Lorenzo Galluzzi,Peter Vandenabeele,John M. Abrams,Emad S. Alnemri,Eric H. Baehrecke,Mikhail V. Blagosklonny,Wafik S. El-Deiry,Pierre Golstein,Pierre Golstein,Douglas R. Green,Michael O. Hengartner,Richard A. Knight,Sharad Kumar,Stuart A. Lipton,Stuart A. Lipton,Stuart A. Lipton,Walter Malorni,Gabriel Núñez,Marcus E. Peter,Juerg Tschopp,Junying Yuan,Mauro Piacentini,Boris Zhivotovsky,Gerry Melino,Gerry Melino +29 more
TL;DR: This study details the 2009 recommendations of the NCCD on the use of cell death-related terminology including ‘entosis’, ‘mitotic catastrophe”,’ ‘necrosis‚ ‘necroptosis‚’ and ‘pyroptotic’.
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Molecular origins of cancer: Lung cancer
TL;DR: From the Departments of Thoracic/Head and Neck Medical Oncology and Clinical Cancer Prevention, University of Texas M.D. Anderson Cancer Center, Houston.
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Insulin and insulin-like growth factor signalling in neoplasia
TL;DR: Epidermiological, clinical and laboratory research methods are being used to investigate novel cancer prevention and treatment strategies related to insulin and IGF signalling, including the use of novel receptor-specific antibodies, receptor kinase inhibitors and AMP-activated protein kinase activators.