Gene Ontology: tool for the unification of biology
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...Annotations typically correspond to an existing repository of knowledge, such as the Gene Ontology database (2)....
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Cites background from "Gene Ontology: tool for the unifica..."
...For instance, Gene Ontology (GO) (Ashburner et al., 2000) annotates genes to biological processes, molecular functions, and cellular components in a directed acyclic graph structure, Kyoto Encyclopedia of Genes and Genomes (KEGG) (Kanehisa et al., 2010) annotates genes to pathways, and Disease…...
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References
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"Gene Ontology: tool for the unifica..." refers background in this paper
...2 ); and the fruitfly Drosophila melanogaster , completed earlier this yea...
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"Gene Ontology: tool for the unifica..." refers background in this paper
...Another use for GO ontologies that is gaining rapid adherence is the annotation of gene-expression data, especially after these have been clustered by similarities in pattern of gene expressio...
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4,254 citations
"Gene Ontology: tool for the unifica..." refers background in this paper
...Functional conservation requires a common language for annotation Nowhere is the impact of the grand biological unification more evident than in the eukaryotes, where the genomic sequences of three model systems are already available (budding yeast, Saccharomyces cerevisiae , completed in 1996 (ref...
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