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Genogroup I picobirnavirus in diarrhoeic foals: can the horse serve as a natural reservoir for human infection?

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TLDR
A PBV strain, PBV/Horse/India/BG-Eq-3/2010, was identified in the faeces of a 10 month old weaned female foal with diarrhoea in January 2010 from Kolkata, India and sequence comparison and phylogenetic analysis revealed close genetic relatedness to a human genogroup IPBV strain detected earlier from the same part of India.
Abstract
Picobirnaviruses (PBV) are small, non-enveloped viruses with a bisegmented double-stranded RNA genome. In this study a PBV strain, PBV/Horse/India/BG-Eq-3/2010, was identified in the faeces of a 10 month old weaned female foal with diarrhoea in January 2010 from Kolkata, India. Surprisingly, sequence comparison and phylogenetic analysis of a short stretch of the RNA dependent RNA polymerase gene revealed close genetic relatedness (> 98% nucleotide identity) to a human genogroup I PBV strain (Hu/GPBV1) detected earlier from the same part of India. Our observations together with earlier findings on genetic relatedness between human and animal PBV warrant further studies on zoonotic potential.

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Journal ArticleDOI

Water quality indicators: bacteria, coliphages, enteric viruses

TL;DR: The potential of human pathogenic viruses as significant indicators of water quality is emerging and has been proposed as suitable indices for the effective identification of such organisms of human origin contaminating water systems.
Journal ArticleDOI

Exploring the virome of diseased horses.

TL;DR: The number of viruses found in horses is expanded, and their genomes are characterized to assist future epidemiological studies of their transmission and potential association with various equine diseases.
Journal ArticleDOI

Animal Picobirnavirus

TL;DR: Pereira et al. as mentioned in this paper presented a review of the veterinary and zoonotic aspects of animal Picobirnavirus infections since its discovery, focusing on the potential role of PBV as either a primary diarrhoeal agent or a potential pathogen in "immunocompetent individuals" or an "innocuous virus" in the intestine.
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Picobirnavirus infections: viral persistence and zoonotic potential

TL;DR: The public health aspects of PBV infection, especially its possible association with zoonosis is analyzed, as well as evidence has been found for genetic relatedness between human and animalPBV strains, suggesting extant crossing points in the ecology and evolution of heterologous PBV strains.
References
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Journal ArticleDOI

Detection of Genogroup I and II human picobirnaviruses showing small genomic RNA profile causing acute watery diarrhoea among children in Kolkata, India.

TL;DR: The short genome profile PBVs associated with acute watery diarrhoea may be another emerging diarrhoeagenic virus in Kolkata, India, where four PBV positives of Genogroup II were detected during this study.
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Identification in porcine faeces of a novel virus with a bisegmented double stranded RNA genome.

TL;DR: The results confirm the circulation among pigs of a novel virus, possibly of vertebrates, with a bisegmented double stranded RNA genome, similar to viruses previously described in humans, wild rats, guinea pigs, pigs, and chickens, for which the name “picobirnavirus” has been proposed.

Short Communication Genogroup I picobirnaviruses in pigs: evidence for genetic diversity and relatedness to human strains

TL;DR: The molecular analysis of porcine PBVs identified in the intestinal content of dead pigs suggested that PBVs exist as quasispecies in the swine alimentary tract and indicated that infection with genogroup I PBVs is common in pigs.
Journal ArticleDOI

Viruses with bisegmented double-stranded RNA in pig faeces.

TL;DR: Viruses similar to the bisegmented double-stranded (ds) RNA picobirnaviruses described in human faeces and the intestinal contents of Oryzomys nigripes rats and guinea pigs were isolated from the Faeces of pigs taken from several areas in the state of Sao Paulo, Brazil.
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