Geographic Patterns of Genome Admixture in Latin American Mestizos
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Cites background from "Geographic Patterns of Genome Admix..."
...Admixed populations often have high variation across individuals in the proportions of ancestry from the various source group...
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"Geographic Patterns of Genome Admix..." refers methods in this paper
...Unfortunately, although it is broadly known that the history of Latin America entailed an extensive admixture of Native PLoS Genetics | www.plosgenetics.org 1 2008 | Volume 4 | Issue 3 | e1000037 Americans, Europeans and Africans, few details are known about this process or about its genetic correlates[16–19]....
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...The expected heterozygosity (I) for the Mestizo was calculated using the expression of Rosenberg and Huang (personal communication): I~c2IAz(1{c) 2IBzc(1{c)(IAzIB) 1zF 1{F Where IA and IB are the observed heterozygosities of European and Native American populations, F the FST estimated between Europeans and Africans, and c the proportion of European ancestry in the Mestizo....
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...Most analyses were carried out using a dataset that also included genotype information for 160 Europeans, 123 Africans and 463 Native Americans (from 26 Amerindian populations, samples size 7–25)....
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...K was varied in order to examine different groupings of Native American populations while considering Europeans and Africans as single independent clusters: K = 3 when grouping all Native American data into a single cluster, K = 7 when Native American populations were grouped into five linguistic stocks and K = 28 when each Native American population was considered independently....
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...We analyzed genotype data for 678 autosomal and 29 Xchromosome microsatellites collected in the Mestizo populations together with similar data available in samples from Europeans, Native Americans and Africans[22,23]....
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"Geographic Patterns of Genome Admix..." refers background in this paper
...Such a sex bias in African admixture has been inferred African Americans from the US[39] but had not been evidenced in Mestizos....
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