Global Epidemiology of Campylobacter Infection
Reads0
Chats0
TLDR
Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come.Abstract:
Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni, there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus. Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.read more
Citations
More filters
Journal ArticleDOI
Agricultural intensification and the evolution of host specialism in the enteric pathogen Campylobacter jejuni.
Evangelos Mourkas,Aidan J. Taylor,Guillaume Méric,Guillaume Méric,Guillaume Méric,Sion C. Bayliss,Ben Pascoe,Leonardos Mageiros,Jessica K. Calland,Matthew D. Hitchings,Anne Ridley,Ana Vidal,Ken J. Forbes,Norval J. C. Strachan,Craig T. Parker,Julian Parkhill,Keith A. Jolley,Alison J. Cody,Martin C. J. Maiden,David J. Kelly,Samuel K. Sheppard,Samuel K. Sheppard +21 more
TL;DR: The nature and timescale of cattle adaptation in the world’s most common enteric bacterial pathogen (Campylobacter jejuni) in the most prolific agricultural mammal (cattle) is explained and genomic plasticity can allow important zoonotic pathogens to exploit altered niches in the face of anthropogenic change is highlighted.
Journal ArticleDOI
Impact of CDT Toxin on Human Diseases
TL;DR: In vitro and in vivo studies have clearly shown that this toxin has a strong effect on cellular physiology (inflammation, immune response modulation, tissue damage).
Journal ArticleDOI
Coadministration of the Campylobacter jejuni N-Glycan-Based Vaccine with Probiotics Improves Vaccine Performance in Broiler Chickens.
Harald Nothaft,Maria Elisa Perez-Muñoz,Goncalo J. Gouveia,Rebbeca M. Duar,Joseph J. Wanford,Lea Lango-Scholey,C. G. Panagos,V. Srithayakumar,Graham Plastow,Colin Coros,Christopher D. Bayliss,Arthur S. Edison,Jens Walter,Christine M. Szymanski,Christine M. Szymanski +14 more
TL;DR: Improved vaccine performance in meat birds by supplementing the vaccine with probiotics and it is demonstrated that C. jejuni colonization levels in chickens are negatively correlated with the abundance of clostridia, another group of common gut microbes.
Book ChapterDOI
Campylobacter in the Food Chain.
TL;DR: This chapter reviews the sources, transmission routes, the mechanisms, and strategies used by Campylobacter to persist in the whole food chain, from farm to fork, and different strategies are recommended for application along the poultry food chain to avoid the public health risk associated with this pathogen.
Journal ArticleDOI
Novel Clinical Campylobacter jejuni Infection Models Based on Sensitization of Mice to Lipooligosaccharide, a Major Bacterial Factor Triggering Innate Immune Responses in Human Campylobacteriosis.
TL;DR: Recent progress made in the development of murine C. jejuni infection models that are based on the abolishment of CR by modulating the murine gut microbiota and by sensitization of mice to LOS support the major role of LOS driven innate immunity in pathogenesis of campylobacteriosis including post-infectious autoimmune diseases.
References
More filters
Journal ArticleDOI
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.
Karen L. Kotloff,James P. Nataro,William C. Blackwelder,Dilruba Nasrin,Tamer H. Farag,Sandra Panchalingam,Yukun Wu,Samba O. Sow,Dipika Sur,Robert F. Breiman,Abu Syed Golam Faruque,Anita K. M. Zaidi,Debasish Saha,Pedro L. Alonso,Boubou Tamboura,Doh Sanogo,Uma Onwuchekwa,Byomkesh Manna,Thandavarayan Ramamurthy,Suman Kanungo,John B. Ochieng,Richard Omore,Joseph Oundo,Anowar Hossain,Sumon Kumar Das,Shahnawaz Ahmed,Shahida Qureshi,Farheen Quadri,Richard A. Adegbola,Richard A. Adegbola,Martin Antonio,M. Jahangir Hossain,Adebayo Akinsola,Inacio Mandomando,Tacilta Nhampossa,Sozinho Acácio,Kousick Biswas,Ciara E. O’Reilly,Eric D. Mintz,Lynette Y. Berkeley,Lynette Y. Berkeley,Khitam Muhsen,Halvor Sommerfelt,Halvor Sommerfelt,Roy M. Robins-Browne,Myron M. Levine +45 more
TL;DR: Interventions targeting five pathogens can substantially reduce the burden of moderate-to-severe diarrhoea and suggest new methods and accelerated implementation of existing interventions (rotavirus vaccine and zinc) are needed to prevent disease and improve outcomes.
Journal ArticleDOI
The functional gastrointestinal disorders and the Rome III process.
TL;DR: Two important processes have occurred to legitimize these conditions, and to increase attention toward the research and clinical care of patients with functional gastrointestinal disorders (FGID), a shift in conceptualizing these disorders from a disease-based, reductionistic model, to a more integrated, biopsychosocial model of illness.
Journal ArticleDOI
Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
Mauro Castellarin,René L. Warren,J. Douglas Freeman,Lisa Dreolini,Martin Krzywinski,Jaclyn Strauss,Rebecca O Barnes,Peter H. Watson,Emma Allen-Vercoe,Richard A. Moore,Robert A. Holt +10 more
TL;DR: Overabundance of Fusobacterium sequences in tumor versus matched normal control tissue is verified by quantitative PCR analysis from a total of 99 subjects, and a positive association with lymph node metastasis is observed.
Journal ArticleDOI
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
Aleksandar Kostic,Dirk Gevers,Chandra Sekhar Pedamallu,Chandra Sekhar Pedamallu,Monia Michaud,Fujiko Duke,Fujiko Duke,Ashlee M. Earl,Akinyemi I. Ojesina,Akinyemi I. Ojesina,Joonil Jung,Adam J. Bass,Adam J. Bass,Josep Tabernero,José Baselga,Chen Liu,Ramesh A. Shivdasani,Shuji Ogino,Bruce W. Birren,Curtis Huttenhower,Curtis Huttenhower,Wendy S. Garrett,Wendy S. Garrett,Matthew Meyerson,Matthew Meyerson +24 more
TL;DR: The composition of the microbiota in colorectal carcinoma is characterized using whole genome sequences from nine tumor/normal pairs and Fusobacterium sequences were enriched in carcinomas, confirmed by quantitative PCR and 16S rDNA sequence analysis of 95 carcinoma/normal DNA pairs.
Journal ArticleDOI
Campylobacter enteritis: a "new" disease.
TL;DR: Campylobacters are a relatively unrecognised cause of acute enteritis, but these findings suggest that they may be a common cause, and poultry may be the primary source of the organism.
Related Papers (5)
The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences
Julian Parkhill,Brendan W. Wren,Karen Mungall,Julian M. Ketley,Carol Churcher,D. Basham,Tracey Chillingworth,Robert L. Davies,Theresa Feltwell,S. Holroyd,Kay Jagels,Andrey V. Karlyshev,Sharon Moule,Mark J. Pallen,Charles W. Penn,Michael A. Quail,Marie-Adèle Rajandream,Kim Rutherford,A. H. M. van Vliet,Sally Whitehead,Bart Barrell +20 more