scispace - formally typeset
Search or ask a question
Journal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

16 Sep 2017-The Lancet (Elsevier)-Vol. 390, Iss: 10100, pp 1211-1259
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
About: This article is published in The Lancet.The article was published on 2017-09-16 and is currently open access. It has received 10401 citations till now. The article focuses on the topics: Mortality rate.
Citations
More filters
Journal ArticleDOI
TL;DR: Authors/Task Force Members: Piotr Ponikowski* (Chairperson) (Poland), Adriaan A. Voors* (Co-Chair person) (The Netherlands), Stefan D. Anker (Germany), Héctor Bueno (Spain), John G. F. Cleland (UK), Andrew J. S. Coats (UK)

13,400 citations

Journal ArticleDOI
Theo Vos1, Theo Vos2, Theo Vos3, Stephen S Lim  +2416 moreInstitutions (246)
TL;DR: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates, and there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries.

5,802 citations

Journal ArticleDOI
TL;DR: The sources and methods used in compiling the cancer statistics in 185 countries are reviewed, and uncertainty intervals are now provided for the estimated sex‐ and site‐specific all‐ages number of new cancer cases and cancer deaths.
Abstract: Estimates of the worldwide incidence and mortality from 36 cancers and for all cancers combined for the year 2018 are now available in the GLOBOCAN 2018 database, compiled and disseminated by the International Agency for Research on Cancer (IARC). This paper reviews the sources and methods used in compiling the cancer statistics in 185 countries. The validity of the national estimates depends upon the representativeness of the source information, and to take into account possible sources of bias, uncertainty intervals are now provided for the estimated sex- and site-specific all-ages number of new cancer cases and cancer deaths. We briefly describe the key results globally and by world region. There were an estimated 18.1 million (95% UI: 17.5-18.7 million) new cases of cancer (17 million excluding non-melanoma skin cancer) and 9.6 million (95% UI: 9.3-9.8 million) deaths from cancer (9.5 million excluding non-melanoma skin cancer) worldwide in 2018.

4,924 citations

Journal ArticleDOI
TL;DR: Just under half a billion people are living with diabetes worldwide and the number is projected to increase by 25% in 2030 and 51% in 2045, with the prevalence higher in urban than rural areas, and in high-income than low-income countries.

4,865 citations

Journal ArticleDOI
TL;DR: In this paper, the authors assess the burden of 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus, and evaluate cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) for 195 countries and territories by age and sex using the Global Burden of Disease study estimation methods.
Abstract: Importance The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required. Objective To assess the burden for 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus. Evidence Review Cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) were evaluated for 195 countries and territories by age and sex using the Global Burden of Disease study estimation methods. Levels and trends were analyzed over time, as well as by the Sociodemographic Index (SDI). Changes in incident cases were categorized by changes due to epidemiological vs demographic transition. Findings In 2016, there were 17.2 million cancer cases worldwide and 8.9 million deaths. Cancer cases increased by 28% between 2006 and 2016. The smallest increase was seen in high SDI countries. Globally, population aging contributed 17%; population growth, 12%; and changes in age-specific rates, −1% to this change. The most common incident cancer globally for men was prostate cancer (1.4 million cases). The leading cause of cancer deaths and DALYs was tracheal, bronchus, and lung cancer (1.2 million deaths and 25.4 million DALYs). For women, the most common incident cancer and the leading cause of cancer deaths and DALYs was breast cancer (1.7 million incident cases, 535 000 deaths, and 14.9 million DALYs). In 2016, cancer caused 213.2 million DALYs globally for both sexes combined. Between 2006 and 2016, the average annual age-standardized incidence rates for all cancers combined increased in 130 of 195 countries or territories, and the average annual age-standardized death rates decreased within that timeframe in 143 of 195 countries or territories. Conclusions and Relevance Large disparities exist between countries in cancer incidence, deaths, and associated disability. Scaling up cancer prevention and ensuring universal access to cancer care are required for health equity and to fulfill the global commitments for noncommunicable disease and cancer control.

4,621 citations

References
More filters
Journal ArticleDOI
TL;DR: In its June 2015 publication, Strategies to improve Cardiac Arrest Survival: A Time to Act, The Institute of Medicine delineated the public health impact and scope of the problem of cardiac arrest in the United States.
Abstract: In its June 2015 publication, Strategies to Improve Cardiac Arrest Survival: A Time to Act , The Institute of Medicine (IOM) delineated the public health impact and scope of the problem of cardiac arrest in the United States. The IOM emphasized that although the survival rate varies widely across

26 citations

Journal ArticleDOI
TL;DR: O paciente hipoxemicos apresentaram maior comprometimento da qualidade de vida, avaliada pelo escore total e pelos escores dos dominios sintomas e impacto do SGRQ, que os pacientes nao hip Oxigenoterapia domiciliar prolongada.
Abstract: OBJETIVO: Avaliar a qualidade de vida relacionada a saude de pacientes com doenca obstrutiva cronica das vias aereas recebendo oxigenoterapia domiciliar prolongada (ODP) por meio de cilindros de oxigenio e comparar estes resultados com os obtidos apos seis meses de modificacao do sistema de fornecimento para concentradores de oxigenio. METODOS: Um total de 45 pacientes, 24 com hipoxemia cronica e 21 sem evidencias de hipoxemia, foram avaliados. Os pacientes com hipoxemia cronica estavam recebendo ODP regularmente durante pelo menos os ultimos seis meses e foram avaliados no momento basal, em uso de cilindro, e apos seis meses de transicao para concentradores. Os pacientes nao hipoxemicos foram avaliados no mesmo intervalo de tempo que os pacientes hipoxemicos. Para avaliar a qualidade de vida foi utilizada a versao validada para lingua portuguesa (Brasil) do Questionario Respiratorio Saint George (Saint George's Respiratory Questionnaire - SGRQ). RESULTADOS: No momento inicial, os pacientes hipoxemicos apresentaram maior comprometimento da qualidade de vida, avaliada pelo escore total e pelos escores dos dominios sintomas e impacto do SGRQ, que os pacientes nao hipoxemicos. Apos seis meses, houve melhora significativa da qualidade de vida dos pacientes hipoxemicos e, neste momento, nao foi encontrada diferenca entre os pacientes com e sem hipoxemia. CONCLUSAO: Nossos achados mostraram que os pacientes com doenca obstrutiva cronica das vias aereas e hipoxemia cronica apresentam prejuizo da qualidade de vida, que essa qualidade de vida pode ser melhorada com o uso regular de ODP e que o sistema de fornecimento de oxigenio tem influencia nessa melhora.

25 citations

Journal ArticleDOI
TL;DR: The evolution of physiological variables was nearly identical in subgroups of patients who had died or were still alive at the time of data collection (T3) and this held particularly true for PAP.
Abstract: In 24 patients with severe chronic obstructive pulmonary disease (COPD), we investigated the evolution of pulmonary volumes, arterial blood gases (ABG) and mean pulmonary artery pressure (PAP), before

22 citations

Journal ArticleDOI
TL;DR: A cross-sectional study estimating the prevalence of five gastrointestinal conditions using MarketScan claims data for 73.1 million enrollees found individuals meeting case definition were more likely to meet the more stringent definition for inclusion in the study cohort.

20 citations

Journal ArticleDOI
TL;DR: In this population, prevalence of heart disease can be estimated from claims data with acceptable accuracy and agreement between claims data and manual review was best in both the development and the validation samples.
Abstract: Agreement between claims data and manual review was best in both the development and the validation samples (Cohen’s 8, 0.92, 95% confidence interval [CI], 0.87–0.97; and Cohen’s 8, 0.94, 95% CI, 0.89–0.98, respectively) when patients with only 1 visit were considered to have heart disease. Conclusion In this population, prevalence of heart disease can be estimated from claims data with acceptable accuracy.

17 citations