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Glossary of Indian Medicinal Plants
01 Jan 1956-
About: The article was published on 1956-01-01 and is currently open access. It has received 5524 citations till now. The article focuses on the topics: Glossary.
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TL;DR: The studies revealed significant and concentration dependent hepatoprotective potential of ‘IF’ as it reversed the majority of the altered hepatic parameters in experimental liver damage in rodents.
Abstract: Iridoid enriched fraction IF from the ethanol-water extract of aerial parts (leaves and stems) of Barleria prionitis Linn. was evaluated for hepatoprotective activity in various acute and chronic animal test models of hepatotoxicity. It afforded significant hepatoprotection against carbon tetrachloride, galactosamine and paracetamol induced hepatotoxicity. Silymarin, was used as reference hepatoprotective. In the safety evaluation study the oral LD50 was found to be more than 3000 mg/kg, with no signs of abnormalities or any mortality observed for 15 days period under observation after single dose of drug administration whereas intraperitoneal LD50 was found to be 2530 mg/kg ± 87 mg/kg. SE (n = 10) in mice. The studies revealed significant and concentration dependent hepatoprotective potential of ‘IF’ as it reversed the majority of the altered hepatic parameters in experimental liver damage in rodents. Copyright © 2005 John Wiley & Sons, Ltd.
59 citations
TL;DR: It is concluded that the extraction of plumbagin from Drosera plants is not commercially feasible.
Abstract: The rapid clonal multiplication of two species of South African Drosera is described. Levels of plumbagin, (5-hydroxy-2-methyl-1,4-naphthoquinone) from in vivo and in vitro grown plants are compared to those present in Plumbago roots. P. auriculata Lam. roots contained more than twice as much plumbagin as in vivo grown D. capensis L. plants which in turn contained more than twice as much as comparable plants of D. natalensis Diels. It is concluded that the extraction of plumbagin from Drosera plants is not commercially feasible.
58 citations
Cites background from "Glossary of Indian Medicinal Plants..."
...Extracts from these plants show antimicrobial [4] and other medicinal properties [2, 10]....
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TL;DR: Findings suggest that the gastroprotective activity of CQE could be mediated possibly through its antioxidant effect as well as by the attenuation of the oxidative mechanism and neutrophil infiltration.
58 citations
TL;DR: In this article, a simple sonochemical method via a green approach was used for the synthesis of C. gigantea leaf extract capped CdS NPs and the obtained materials were thoroughly characterized by various physicochemical techniques such as UV-vis DRS, PL, XRD, ATRFTIR, SEM, TEM, Raman, zeta potential and DLS.
Abstract: Here, we report for the synthesis of C. gigantea leaf extract capped CdS NPs by a simple sonochemical method via a green approach. The obtained materials were thoroughly characterized by various physicochemical techniques such as UV–vis DRS, PL, XRD, ATR-FTIR, SEM, TEM, Raman, zeta potential and DLS. The TEM image shows the average particle size of CdS NPs as 20 nm. The photocatalytic performance of CdS NPs on the degradation of MB and EY under sunlight irradiation is investigated. The synthesized CdS NPs attain an efficient degradation efficiency of MB and EY dyes under 60 min of sunlight irradiation. To investigate the selectivity of metal ions, Pb 2+ , Sn 2+ and Hg 2+ were studied for their sensing property in a nanomolar concentration by spectrofluorometrically. The antimicrobial property of CdS NPs was also investigated. Our work suggests that prepared CdS NPs could be a potential photocatalyst, a sensor, and an active antimicrobial agent.
58 citations
TL;DR: This review focuses on the anticancer role of some of colchicine-based derivatives and their therapeutic importance.
Abstract: Colchicine, the main alkaloid of the poisonous plant meadow saffron (Colchicum autumnale L.), is a classical drug used for the treatment of gout and familial Mediterranean fever. Although colchicine is not clinically used to treat cancer because of toxicity, it exerts antiproliferative effects through the inhibition of microtubule formation by blocking the cell cycle at the G2/M phase and triggering apoptosis. Colchicine can still be used as a lead compound for the generation of potential anticancer drugs. Thus, numerous analogues of colchicine have been synthesized in the hope of developing novel, useful drugs with more favourable pharmacological profiles. Several colchicine semisynthetics are less toxic than colchicine and research is being carried out on effective, less toxic colchicine semisynthetic formulations with potential drug-delivery strategies directly targeting multiple solid cancers. This review focuses on the anticancer role of some of colchicine-based derivatives and their therapeutic importance.
58 citations