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Glossary of Indian Medicinal Plants
01 Jan 1956-
About: The article was published on 1956-01-01 and is currently open access. It has received 5524 citations till now. The article focuses on the topics: Glossary.
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TL;DR: Since the post-coital contraceptive effect of neemOil seems to be non-hormonal, neem oil would be expected to elicit less side effects than the steroidal contraceptives.
36 citations
TL;DR: The ethanol and water extracts of Capparis zeylanica leaves showed dose-dependent and significant increases in pain threshold in tail-immersion test and preliminary phytochemical screening showed the presence of alkaloids, flavonoids, saponins glycosides, terpenoids, tannins, proteins and carbohydrates.
36 citations
TL;DR: Results showed that FPBA extract not only possess significant antioxidant and genoprotective property but also is able to attenuate the enzymatic activity of HMG-CoA reductase, which might suggest its role in combating various oxidative stress-related diseases, including atherosclerosis.
Abstract: Hypercholesterolemia-induced oxidative stress has been strongly implicated in the pathogenesis of atherosclerosis, which is one of the major causes of mortality worldwide. The current work, for the first time, accounts the antioxidant, genoprotective, antilipoperoxidative, and HMG-CoA reductase (EC 1.1.1.34) inhibitory properties of traditional medicinal plant, Ficus palmata Forsk. Our result showed that among sequentially extracted fractions of Ficus palmata Forsk, FPBA (F. palmata bark aqueous extract) and FPLM (F. palmata leaves methanolic extract) extracts have higher phenolic content and also exhibited significantly more radical scavenging (DPPH and Superoxide) and antioxidant (FRAP) capacity. Moreover, FPBA extract also exhibited significantly higher inhibition of lipid peroxidation assay. Additionally, results showed almost complete and partial protection of oxidatively damaged DNA by these plant extracts when compared to mannitol. Furthermore, our results showed that FPBA extract (IC50 = 9.1 ± 0.61 µg/mL) exhibited noteworthy inhibition of HMG-CoA reductase activity as compared to other extracts, which might suggest its role as cardioprotective agent. In conclusion, results showed that FPBA extract not only possess significant antioxidant and genoprotective property but also is able to attenuate the enzymatic activity of HMG-CoA reductase, which might suggest its role in combating various oxidative stress-related diseases, including atherosclerosis.
36 citations
TL;DR: Administration of TD orally for 45 days to HCC-bearing animals significantly reduced the tissue damage accompanied by restoration of the levels of antioxidants, which contribute to its therapeutic effect in AFB1-induced HCC in rats.
Abstract: Hepatocellular carcinoma (HCC) is one of the most fatal cancers due to delayed diagnosis and lack of effective treatment options. Significant exposure to Aflatoxin B1 (AFB1), a potent hepatotoxic and hepatocarcinogenic mycotoxin, plays a major role in liver carcinogenesis through oxidative tissue damage and p53 mutation. The present study emphasizes the anticarcinogenic effect of Tridham (TD), a polyherbal traditional medicine, on AFB1-induced HCC in male Wistar rats. AFB1-administered HCC-bearing rats (Group II) showed increased levels of lipid peroxides (LPOs), thiobarbituric acid substances (TBARs), and protein carbonyls (PCOs) and decreased levels of enzymic and nonenzymic antioxidants when compared to control animals (Group I). Administration of TD orally (300 mg/kg body weight/day) for 45 days to HCC-bearing animals (Group III) significantly reduced the tissue damage accompanied by restoration of the levels of antioxidants. Histological observation confirmed the induction of tumour in Group II animals and complete regression of tumour in Group III animals. This study highlights the potent antioxidant properties of TD which contribute to its therapeutic effect in AFB1-induced HCC in rats.
36 citations
Cites background from "Glossary of Indian Medicinal Plants..."
...) possesses antibacterial, antifungal, antiviral, and several other pharmacological properties [35]....
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TL;DR: The study suggests the possible development of AGN as a therapeutic agent in the treatment of arthritis by the modulation of the host immune response.
Abstract: Objective and design
The purpose of this study was to elucidate the probable mechanism for the anti-arthritic activity of agnuside (AGN), a compound isolated from the leaf extract of Vitex negundo.
36 citations
Cites background from "Glossary of Indian Medicinal Plants..."
...The leaves are astringent, febrifuge, sedative, tonic and vermifuge [1, 2]....
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