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Glossary of Indian Medicinal Plants

About: The article was published on 1956-01-01 and is currently open access. It has received 5524 citations till now. The article focuses on the topics: Glossary.
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Journal ArticleDOI
TL;DR: In this article, the effect of leaf extract of Ocimum sanctum on specific and non-specific immune responses and disease resistance against Aeromonas hydrophila was investigated in Oreochromis mossambicus.
Abstract: Effect of leaf extract of Ocimum sanctum on (i) the specific and non-specific immune responses and (ii) disease resistance against Aeromonas hydrophila was investigated in Oreochromis mossambicus. Sheep red blood cells (SRBC) and Heat aggregated bovine serum albumin (HA-BSA) were used as antigens for specific and non-specific immune response studies, respectively. Antigens were administered through intraperitoneal route. Anti-SRBC antibody titres were determined by direct haemagglutination and anti-bacterial antibodies were determined by bacterial agglutination. Nitroblue tetrazolium (NBT) assay was used to determine neutrophil activity. Disease resistance was measured in terms of relative percent survival (RPS). The immunostimulatory effect of the leaf extract of O. sanctum, when administered through intraperitoneal and oral routes was obvious. Leaf extract of O. sanctum, when administered intraperitoneally, stimulated both antibody response and neutrophil activity. Dietary intake of O. sanctum also enhanced the antibody response and disease resistance against A. hydrophila. Possibility of using O. sanctum as immunostimulant in the maintenance of finfish health in intensive freshwater aquaculture is suggested.

172 citations


Cites background from "Glossary of Indian Medicinal Plants..."

  • ...The leaf ofO. sanctumhas been shown to contain water soluble phenolic compounds, and various other constituents such as eugenol, methyl eugenol and caryophyllene (Chopra et al., 1956) that might act as a potential immunostimulant....

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  • ...sanctumhas been shown to contain water soluble phenolic compounds, and various other constituents such as eugenol, methyl eugenol and caryophyllene (Chopra et al., 1956) that might act as a potential immunostimulant....

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Journal ArticleDOI
TL;DR: Experimental evidence suggests that because of its antioxidant activity, this Ayurvedic drug may be useful in the treatment of human pathologies in which free radical production plays a key role.
Abstract: Bacopa monniera L. (family Scrophulariaceae) (BM) is an Ayurvedic medicine, clinically used for memory enhancing, epilepsy, insomnia and as a mild sedative. In this work, the free radical scavenging capacity of a methanol extract of BM and the effect on DNA cleavage induced by H2O2 UV-photolysis was investigated. In addition, we examined whether this plant extract is capable of reducing the hydrogen peroxide-induced cytotoxicity and DNA damage in human non-immortalized fibroblasts. It showed a dose-dependent free radical scavenging capacity and a protective effect on DNA cleavage. These results were confirmed by a significant protective effect on H2O2-induced cytoxicity and DNA damage in human non-immortalized fibroblasts. The antioxidant capacity of BM may explain, at least in part, the reported antistress, immunomodulatory, cognition-facilitating, antiinflammatory and antiaging effects produced by it in experimental animals and in clinical situations and may justify further investigation of its other beneficial properties. Moreover, this experimental evidence suggests that because of its antioxidant activity, this Ayurvedic drug may be useful in the treatment of human pathologies in which free radical production plays a key role.

171 citations


Cites background from "Glossary of Indian Medicinal Plants..."

  • ...Bacopa monniera is reputed to be a nerve tonic in Indian traditional medicine (Chopra et al., 1969; Chunekar, 1960; Satyavati et al., 1976)....

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Journal ArticleDOI
TL;DR: The aqueous extract of T. chebula acts as a potent antioxidant and since it is able to protect cellular organelles from the radiation-induced damage, it may be considered as a probable radioprotector.

171 citations

Journal ArticleDOI
TL;DR: In this paper, electron beam irradiation of lotus seeds has been used to preserve the nutritional and antinutritional properties of raw and electron beam-irradiated (doses: 0, 2.5, 5, 7.5 and 10, 15, 15 and 30 kGy) lotsus seeds.

169 citations

Journal ArticleDOI
TL;DR: In vivo, using the DBA2/P815 (H2d) mouse model, the results clearly showed that the injection of the essential oil into the tumor site significantly inhibited solid tumor development and improved mouse survival.
Abstract: The objective of the present study was to evaluate the in vitro and invivo anti-cancer effect of Nigella sativa L. seed extracts. The essentialoil (IC 50 = 0.6%, v/v) and ethyl acetate (IC 50 = 0.75%) extracts weremore cytotoxic against the P815 cell line than the butanol extract (IC 50 = 2%). Similar results were obtained with the Vero cell line. Althoughall extracts had a comparable cytotoxic effect against the ICO1 cellline, with IC 50 values ranging from 0.2 to 0.26% (v/v), tests on theBSR cell line revealed a high cytotoxic effect of the ethyl acetateextract (IC 50 = 0.2%) compared to the essential oil (IC 50 = 1.2%).These data show that the cytotoxicity of each extract depends on thetumor cell type. In vivo , using the DBA2/P815 (H 2d ) mouse model, ourresults clearly showed that the injection of the essential oil into thetumor site significantly inhibited solid tumor development. Indeed, onthe 30th day of treatment, the tumor volume of the control animals was2.5 ± 0.6 cm

165 citations