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Glossary of Indian Medicinal Plants
01 Jan 1956-
About: The article was published on 1956-01-01 and is currently open access. It has received 5524 citations till now. The article focuses on the topics: Glossary.
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TL;DR: SPA showed dose-dependent action in all the experimental models and indicates that SPA has significant antiinflammatory and analgesic properties.
Abstract: OBJECTIVE: To evaluate the antiinflammatory and analgesic activities of the aqueous extract of Spilanthes acmella (SPA) in experimental animal models. MATERIAL AND METHODS: SPA was evaluated for antiinflammatory action by carrageenan-induced rat paw edema. The analgesic activity was tested by acetic acid-induced writhing response in albino mice and tail flick method in albino rats. RESULTS: The aqueous extract of SPA in doses of 100, 200 and 400 mg/kg showed 52.6, 54.4 and 56.1% inhibition of paw edema respectively at the end of three hours and the percentage of protection from writhing was 46.9, 51.0 and 65.6 respectively. In the tail flick model, the aqueous extract of SPA in the above doses increased the pain threshold significantly after 30 min, 1, 2 and 4 h of administration. SPA showed dose-dependent action in all the experimental models. CONCLUSION: The present study indicates that SPA has significant antiinflammatory and analgesic properties.
149 citations
Cites background from "Glossary of Indian Medicinal Plants..."
...Spilanthes acmella [SPA] (Bengali-Akarkara, AssamesePirazha, Manipuri-Maanja-lei, Telegu-Maratitige) is an indigenous herb belonging to the family Compositae.1 It is grown as an annual herb throughout the tropics....
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...Spilanthes acmella [SPA] (Bengali-Akarkara, AssamesePirazha, Manipuri-Maanja-lei, Telegu-Maratitige) is an indigenous herb belonging to the family Compositae.(1) It is grown as an annual herb throughout the tropics....
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TL;DR: Coriander plays a protective role against the deleterious effects in lipid metabolism in biochemical parameters in 1,2-dimethyl hydrazine induced colon cancer in rats.
147 citations
Cites background from "Glossary of Indian Medicinal Plants..."
...Most spices are known to be a source of many vitamins and domestic remedy for many of the human disorders (Chopra et al., 1956; Nadkarni and Nadkarni, 1976)....
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TL;DR: Bark extract is more effective than melatonin, vitamin E, desferrioxamine and alpha-phenyl N-tert butylnitrone, the known antioxidants having antiulcer effect and well tolerated by rats with no significant adverse effect.
147 citations
TL;DR: In the course of bio‐assay guided fractionation, emodin and physcion were isolated for the first time from the stem‐bark of V. madraspatana and found to be more effective, showing an MIC of 70 µg/mL compared with streptomycin and penicillin G used as standards.
Abstract: The antibacterial activity of the extracts of Ventilago madraspatana stem-bark, Rubia cordifolia root and Lantana camara root-bark, prepared with solvents of different polarity, was evaluated by the agar-well diffusion method. Twelve bacteria, six each of gram-positive and gram-negative strains, were used in this study. Chloroform and ethanol extracts of V. madraspatana showed broad-spectrum activity against most of the bacteria except S. aureus, E. coli and V. cholerae. On the other hand, the activity of the chloroform and methanol extracts of R. cordifolia and L. camara was found to be more specific towards the gram-positive strains, although gram-negative P. aeruginosa was also inhibited by the methanol extracts of both these plants in a dose dependent manner. The water extracts of V. madraspatana and L. camara were found to be inactive, while that of R. cordifolia was significantly active against B. subtilis and S. aureus compared with streptomycin and penicillin G used as standards. In the course of bio-assay guided fractionation, emodin and physcion were isolated for the first time from the stem-bark of V. madraspatana. It was noteworthy to find the MICs of emodin in the range 0.5-2.0 microg/mL against three Bacillus sp. Both the anthraquinonoid compounds inhibited P. aeruginosa, emodin being more effective, showing an MIC of 70 microg/mL.
147 citations
TL;DR: The effect produced by the extract ointment, in terms of wound contracting ability, wound closure time, regeneration of tissues at wound site, tensile strength of the wound and histopathological characteristics were comparable to those of a standard drug nitrofurazone ointments.
146 citations