Journal Article•
Gluconic Acid: Properties, Applications and Microbial Production
15 Jun 2006-Food Technology and Biotechnology (Prehrambeno-biotehnološki fakultet, Sveučilište u Zagrebu)-Vol. 44, Iss: 2, pp 185-195
TL;DR: Gluconic acid is a mild organic acid derived from glucose by a simple oxidation reaction, the principal being sodium gluconate, which has wide applications in food and pharmaceutical industry.
Abstract: Summary Gluconic acid is a mild organic acid derived from glucose by a simple oxidation reaction. The reaction is facilitated by the enzyme glucose oxidase (fungi) and glucose dehydrogenase (bacteria such as Gluconobacter). Microbial production of gluconic acid is the preferred method and it dates back to several decades. The most studied and widely used fermentation process involves the fungus Aspergillus niger. Gluconic acid and its derivatives, the principal being sodium gluconate, have wide applications in food and pharmaceutical industry. This article gives a review of microbial gluconic acid production, its properties and applications.
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TL;DR: In this article, the potential of lignocellulosic biomass as an alternative platform to fossil resources has been analyzed and a critical review provides insights into the potential for LBS.
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Cites background from "Gluconic Acid: Properties, Applicat..."
...Several reviews describe organic acid biosynthesis and excretion mechanisms in bacteria and fungi (Ramachandran et al., 2006; Sauer et al., 2008) and these issues are not addressed in detail here....
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TL;DR: This poster presents a probabilistic procedure to characterize the response of the immune system to x-ray diffraction and three different types of deposits are confirmed to be Na6(CO3), Na4(SO4) and Na2(SO3).
Abstract: the National Natural Science Foundation of China (21073208);the Chinese Academy of Sciences
616 citations
References
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TL;DR: SSF processes offer potential advantages in bioremediation and biological detoxification of hazardous and toxic compounds and appear to be a promising one for the production of value-added ‘low volume-high cost’ products such as biopharmaceuticals.
1,059 citations
Journal Article•
TL;DR: This review focuses on the production of various industrial enzymes by SSF processes, and an illustrative survey is presented on various individual groups of enzymes such as cellulolytic, pectinolytics, ligninolytic, amylolytic and lipolytic enzymes.
Abstract: Enzymes are among the most important products. obtained for human needs through microbial sources. A large number of industrial processes in the areas of industrial, environmental and food biotechnology utilize enzymes at some stage or the other. Current developments in biotechnology are yielding new applications for enzymes. Solid state fermentation (SSF) holds tremendous potential for the production of enzymes. Tt can be of special interest in those processes where the crude fermented products may be used directly as enzyme sources. This review focuses on the production of various industrial enzymes by SSF processes. Following a brief discussion of the micro-organisms and the substrates used in SSF systems, and aspects of the design of fermenter and the factors affecting production of enzymes, an illustrative survey is presented on various individual groups of enzymes such as cellulolytic, pectinolytic, ligninolytic, amylolytic and lipolytic enzymes, etc.
912 citations
TL;DR: In this paper , a simple low-cost surface plasmon resonance (SPR)-sensing cartridge based on a loop-mediated isothermal amplification (LAMP) method for the on-site detection of the hepatitis B virus (HBV) was constructed, including a novel SPRLAMP sensing cartridge integrating a polymethyl methacrylate (PMMA) micro-reactor with a polycarbonate (PC)-based prism coated with a 50 nm Au film.
Abstract: In this study, we report a simple, low-cost surface plasmon resonance (SPR)-sensing cartridge based on a loop-mediated isothermal amplification (LAMP) method for the on-site detection of the hepatitis B virus (HBV). For LAMP detection, a SPR based LAMP sensing system (SPRLAMP) was constructed, including a novel SPRLAMP sensing cartridge integrating a polymethyl methacrylate (PMMA) micro-reactor with a polycarbonate (PC)-based prism coated with a 50 nm Au film. First, we found that the change of refractive index of the bulk solution was approximately 0.0011 refractive index (RI) units after LAMP reaction. The PC-based prism’s linearity and thermal responses were compared to those of a traditional glass prism to show that a PC-based prism can be used for SPR measurement. Finally, the HBV template mixed in the 10 (cid:2) l LAMP solution could be detected by SPRLAMP system in 17 min even at the detection-limited concentration of 2 fg/ml. We also analyzed the correlation coefficients between the initial concentrations of HBV DNA templates and the system response ( (cid:2) RU) at varying amplification times to establish an optimal amplification time endpoint of 25 min ( R 2 = 0.98). In conclusion, the LAMP reaction could be detected with the SPRLAMP sensing cartridge based on direct sensing of the bulk refractive index.
682 citations
498 citations
"Gluconic Acid: Properties, Applicat..." refers background in this paper
...The native enzyme is glycosylated, with a carbohydrate mass percentage of 16–25 % (43,44)....
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TL;DR: In vitro gluconic acid formation and phosphate solubilization from sparingly soluble phosphorus sources by two strains of the plant growth-promoting bacteria A. brasilense and one strain of A. lipoferum JA4 are reported, which is the first report of in vitro glUconic Acid production and direct phosphate solUBilization by A. Brasilense.
Abstract: In vitro gluconic acid formation and phosphate solubilization from sparingly soluble phosphorus sources by two strains of the plant growth-promoting bacteria A. brasilense (Cd and 8-I) and one strain of A. lipoferum JA4 were studied. Strains of A. brasilense were capable of producing gluconic acid when grown in sparingly soluble calcium phosphate medium when their usual fructose carbon source is amended with glucose. At the same time, there is a reduction in pH of the medium and release of soluble phosphate. To a greater extent, gluconic acid production and pH reduction were observed for A. lipoferum JA4. For the three strains, clearing halos were detected on solid medium plates with calcium phosphate. This is the first report of in vitro gluconic acid production and direct phosphate solubilization by A. brasilense and the first report of P solubilization by A. lipoferum. This adds to the very broad spectrum of plant growth-promoting abilities of this genus.
313 citations