Journal ArticleDOI
Glucose-sensitive field effect transistor using totally synthetic compounds
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TLDR
In this article, a field effect transistor (FET)-based glucose sensor was fabricated using 3-acrylamidophenylboronic acid (3-ACYLBP) to detect the change in the glucose concentration in the milieu.Abstract:
A field effect transistor (FET)-based glucose sensor was fabricated As a totally synthetic and thus stable glucose-sensing moiety, 3-acrylamidophenylboronic acid was chemically introduced onto the FET gate surface in the form of a thin copolymer gel layer Excellent transistor characteristics were confirmed even after the surface modification, ensuring validity of the modification procedure herein developed Glucose-induced changes in the FET’s electric characteristics were obtained in quantitative as well as reversible manners It was also demonstrated that the prepared FET is able to continuously perceive the change in the glucose concentration in the milieu The detected signals were attributed to the faction change of the gate-introduced phenyborate anions, also presumably involving other parameter changes such as permittivity and conductivity The use of the fabricated FET could further be extended to the construction of stable, readily minutualizable, and label-free carbohydrate molecule-sensing systemsread more
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Electrochemical and optical sugar sensors based on phenylboronic acid and its derivatives
TL;DR: In this paper, a review of electrochemical and optical sugar sensors based on phenylboronic acid (PBA) and its derivatives as recognition components is reviewed, where PBA-modified electrodes have been constructed as reagentless electrochemical sensors, where PBAs are immobilized on the surface of metal and carbon electrodes through mainly two routes: as a self-assembled monolayer film and as a polymer thin film.
Journal ArticleDOI
Enzyme-Free Sugar Sensing in Microfluidic Channels with an Affinity-Based Single-Wall Carbon Nanotube Sensor
TL;DR: The identification of the mechanism along with the tunability of the chemical coupling and the cost-effective integration in microchannels constitute a solid basis for the entry of nanotube-based sensors in lab-on-a-chip applications.
Journal ArticleDOI
The development of boronic acids as sensors and separation tools
John S. Fossey,Francois D'Hooge,Jean M. H. van den Elsen,Marta P. Pereira Morais,Sofia I. Pascu,Steven D. Bull,Frank Marken,A. Toby A. Jenkins,Yun-Bao Jiang,Tony D. James +9 more
TL;DR: This review provides a somewhat-personal perspective of developments in boronic-acid-mediated sensing and separation, placed in the context of the seminal works of others in the area, as well as offering a concise summary of the contributions of the co-authors.
Journal ArticleDOI
An extended-gate type organic field effect transistor functionalised by phenylboronic acid for saccharide detection in water.
Tsuyoshi Minami,Tsukuru Minamiki,Yuki Hashima,Daisuke Yokoyama,Tomohito Sekine,Kenjiro Fukuda,Daisuke Kumaki,Shizuo Tokito +7 more
TL;DR: The response patterns of the monosaccharides are significantly different, suggesting that OFET devices can successfully read out the saccharide recognition behaviour of boronic acids and be potentially applied to healthcare devices modified with supramolecular receptors.
Journal ArticleDOI
Recent progress in electrochemical biosensors based on phenylboronic acid and derivatives.
TL;DR: This review provides an overview of recent progress made in the development of electrochemical biosensors based on phenylboronic acid and its derivatives and suggests PBA-based F(-) ion sensors may be useful if reagentless sensors can be developed.
References
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Collapse of Gels and the Critical Endpoint
TL;DR: In this article, the authors explain the collapse of polyacrylamide gels in terms of mean field theory based on the extension of Flory's formula for free energy of gels.
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Volume‐phase transitions of ionized N‐isopropylacrylamide gels
TL;DR: In this article, the authors measured the equilibrium swelling curves of Nisopropylacrylamide (NIPA) gel and a series of its ionized counterparts as a function of temperature.
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Chiral discrimination of monosaccharides using a fluorescent molecular sensor
TL;DR: The chiral discrimination of D- and L -monosaccharides is reported using a designed receptor molecule that acts as a sensor by virtue of its fluorescent response to binding of the guest species, enabling them to be distinguished.
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Electronic detection of DNA by its intrinsic molecular charge
TL;DR: The selective and real-time detection of label-free DNA using an electronic readout demonstrates the most direct and simple translation of genetic information to microelectronics.