Glycosylation Defects and Virulence Phenotypes of Leishmania mexicana Phosphomannomutase and Dolicholphosphate-Mannose Synthase Gene Deletion Mutants
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...rich media has recently been generated (114)....
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"Glycosylation Defects and Virulence..." refers methods in this paper
...Total protein of cell lysates was estimated according to Peterson ( 35 )....
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"Glycosylation Defects and Virulence..." refers background in this paper
...(1), LPG; (2), PPG phosphoglycans; (3), protein GPI anchor; (4), GIPL iM3 (as an example); (5), protein N-glycan....
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...mexicana DPMS lack the three surface glycoconjugates LPG, gp63, and GIPLs, which have been described as major virulence factors in Leishmania (3, 8, 38), the infectivity of this particular mutant to macrophages and mice is very surprising....
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334 citations
"Glycosylation Defects and Virulence..." refers background in this paper
...In humans, two enzymes with PMM activity, PMM1 and PMM2, have been cloned and characterized (27, 28)....
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