Granular cell tumour of the breast: A rare presentation of a breast mass in an elderly female with a subsequent breast cancer diagnosis
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TLDR
A 74-year-old female patient presented with a hard breast mass and dimpling with a clinical suspicion of a carcinoma, Histological evaluation revealed a granular cell tumour.Abstract:
A 74-year-old female patient presented with a hard breast mass and dimpling with a clinical suspicion of a carcinoma. Histological evaluation revealed a granular cell tumour. Granular cell tumour is a rare neoplasm, mostly benign in origin that may arise in every body site, 5%-15% of cases occur in the breast. It is strongly suggested that granular cell tumours origin is Schwann cells. Clinically, granular cell tumours presentation may mimic mammary carcinoma and their similar features on mammography and ultrasound make it difficult to differentiate between them.read more
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References
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Über Myome: ausgehend von der quergestreiften willkürlichen Muskulatur
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Granular cell tumor: A clinicopathologic study of 110 patients
Ernest E. Lack,Ernest E. Lack,G F Worsham,Callihan,B E Crawford,S Klappenbach,G Rowden,Byungkyu Chun +7 more
TL;DR: The clinicopathologic features of 118 granular cell tumors encountered at two affiliated hospitals were reviewed and it was found that Schwann cell origin is favored in most cases.
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Granular Cell Tumor of the Breast: A Series of 17 Cases and Review of the Literature
TL;DR: The demographics and clinical features, the radiologic and pathologic features as well as the immunohistochemistry are discussed and this series of 17 breast GCT cases represent the largest series published to date.
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Malignant granular cell tumor: A look into the diagnostic criteria
TL;DR: A preliminary study showed similar selectivity of two more reproducible criteria in the classification of cases of GCT with potential aggressive behavior, preserving a role for Ki-67 in difficult cases, however, metastases remain the sole definite criterion for malignancy.
Journal ArticleDOI
Granular cell tumour of the breast
TL;DR: Granular cell tumour of the breast (GCTB) is a rare tumour which arises from Schwann cells which has a distinctive granular eosinophilic cytoplasm associated with typical nuclei and abundant lysosomes and is associated with a good prognosis.