Journal ArticleDOI
Green nanomedicine: the path to the next generation of nanomaterials for diagnosing brain tumors and therapeutics?
Ebrahim Mostafavi,Ebrahim Mostafavi,Ebrahim Mostafavi,David Medina-Cruz,Ada Vernet-Crua,Junjiang Chen,Jorge L. Cholula-Díaz,Grégory Guisbiers,Thomas J. Webster +8 more
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TLDR
An overview of the current situation for treating brain tumors using nanotechnological-based approaches is introduced, and some of the latest advances in the application of green nanomaterials (NMs) for the effective targeting of brain tumors are presented.Abstract:
Introduction: Current brain cancer treatments, based on radiotherapy and chemotherapy, are sometimes successful, but they are not free of drawbacks.Areas covered: Traditional methods for the treatment of brain tumors are discussed here with new solutions presented, among which the application of nanotechnology has demonstrated promising results over the past decade. The traditional synthesis of nanostructures, which relies on the use of physicochemical methodologies are discussed, and their associated concerns in terms of environmental and health impact due to the production of toxic by-products, need for toxic catalysts, and their lack of biocompatibility are presented. An overview of the current situation for treating brain tumors using nanotechnological-based approaches is introduced, and some of the latest advances in the application of green nanomaterials (NMs) for the effective targeting of brain tumors are presented.Expert opinion: Green nanotechnology is introduced as a potential solution to toxic NMs through the application of environmentally friendly and cost-effective protocols using living organisms and biomolecules. The current status of this field, such as those involving clinical trials, is included, and the possible limitations of green-NMs and potential ways to avoid those limitations are discussed so that the field can potentially evolve.read more
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Antineoplastic activity of biogenic silver and gold nanoparticles to combat leukemia: Beginning a new era in cancer theragnostic
Ebrahim Mostafavi,Atefeh Zarepour,Hamed Barabadi,Ali Zarrabi,Linh B. Truong,David Medina-Cruz +5 more
TL;DR: In this article , a review explores recent advances in green synthesized nanomaterials and their potential use against leukemia, especially focusing on silver (Ag) and gold (Au) nanostructures.
Journal ArticleDOI
Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance
Milad Ashrafizadeh,Hamidreza Saebfar,Mohammad Hossein Gholami,Kiavash Hushmandi,Amirhossein Zabolian,Pooria Bikarannejad,M. Hashemi,Salman Daneshi,Sepideh Mirzaei,Esmaeel Sharifi,Alan Prem Kumar,Haroon Khan,Hamid Heydari Sheikh Hossein,Massoud Vosough,Navid Rabiee,Vijay Thakur Kumar,Pooyan Makvandi,Yogendra Kumar Mishra,Franklin R. Tay,Yuzhuo Wang,Ali Zarrabi,Gorka Orive,Ebrahim Mostafavi +22 more
TL;DR: The graphene oxide nanomaterials for doxorubicin delivery in improving its cytotoxicity, providing a platform for co-delivery, theranostic application and preventing drug resistance development are provided.
Journal ArticleDOI
Bioengineering of green-synthesized silver nanoparticles: In vitro physicochemical, antibacterial, biofilm inhibitory, anticoagulant, and antioxidant performance.
Niloufar Talank,Hamed Morad,Hamed Barabadi,Faraz Mojab,Salimeh Amidi,Farzad Kobarfard,Mohammad Ali Mahjoub,Kamyar Jounaki,Neda Mohammadi,Ghazal Salehi,Milad Ashrafizadeh,Ebrahim Mostafavi +11 more
TL;DR: In this paper , the authors investigated the bioengineering of silver nanoparticles (AgNPs) and evaluated their physicochemical, antibacterial, biofilm inhibitory, anticoagulant, and antioxidant performance.
Journal ArticleDOI
Recent Advances in Green Synthesis of Ag NPs for Extenuating Antimicrobial Resistance
Simerjeet Parmar,Harwinder Kaur,Jagpreet Singh,Avtar S. Matharu,Seeram Ramakrishna,Mikhael Bechelany +5 more
TL;DR: This review evaluates recent advances in biological approaches for Ag NPs, and their antimicrobial potential of Ag-nanostructures-based effective platform for alleviating AMR is evaluated.
Journal ArticleDOI
Selenium Nanomaterials to Combat Antimicrobial Resistance.
TL;DR: A review of the latest advances in the synthesis of selenium nanoparticles and their progress as antimicrobial agents using traditional and biogenic approaches is presented in this article, where the use of nanomaterials is presented as a suitable solution.
References
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Journal ArticleDOI
Cancer statistics, 2019.
TL;DR: The overall cancer death rate dropped continuously from 1991 to 2016 by a total of 27%, translating into approximately 2,629,200 fewer cancer deaths than would have been expected if death rates had remained at their peak.
Journal ArticleDOI
Structure and function of the blood–brain barrier
TL;DR: The structure and function of the BBB is summarised, the physical barrier formed by the endothelial tight junctions, and the transport barrier resulting from membrane transporters and vesicular mechanisms are described.
Journal ArticleDOI
The Blood–Brain Barrier
Richard Daneman,Alexandre Prat +1 more
TL;DR: Understanding how these different cell populations interact to regulate the barrier properties is essential for understanding how the brain functions during health and disease.
Journal ArticleDOI
Biological synthesis of metallic nanoparticles.
TL;DR: This review provides an overview of various methods of synthesis of metallic nanoparticles by biological means and indicates that a promising approach to achieve this objective is to exploit the array of biological resources in nature.
Journal ArticleDOI
Cancer and radiation therapy: current advances and future directions.
TL;DR: Significant advances in the techniques of radiation treatment and progress made in understanding the biology of cancer cell responses to radiation will endeavor to increase the survival and reduce treatment side effects for cancer patients.