Guideline for the laboratory diagnosis of functional iron deficiency.
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"Guideline for the laboratory diagno..." refers background in this paper
...In patients treated with ESAs for the anaemia associated with CKD, the response rate improves when intravenous rather than oral iron supplements are given, and often allows a reduction in the ESA dose (Nemeth et al, 2004; van Wyck et al, 2004; Henry, 2010; Qunibi et al, 2010)....
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Additional excerpts
...The variable received US Federal Drug Administration approval in 1997 and was incorporated into the revised European Best Practice Guidelines for the management of patients with chronic renal failure (Locatelli et al, 2004)....
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"Guideline for the laboratory diagno..." refers background in this paper
...The major clinical role of the assay is in differentiating the anaemia of iron lack from that caused by inflammation, which has little or no effect on sTfR values, and in detecting the presence of iron lack when the two coexist (Ferguson et al, 1992; Punnonen et al (1997)....
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...The TfR index, a ratio of the ferritin concentration to that of sTfR (Punnonen et al, 1997), was found to be superior to ferritin alone in predicting response to intravenous iron in renal patients on long-term ESA therapy (Chen et al, 2006)....
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