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Journal ArticleDOI

Gut Microbiota Dysbiosis in Postweaning Piglets: Understanding the Keys to Health

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TLDR
Nonantimicrobial alternatives, such as zinc oxide, essential oils, and prebiotics or probiotics, which are currently evaluated to restore intestinal balance and allow a better management of the crucial weaning transition are focused on.
About
This article is published in Trends in Microbiology.The article was published on 2017-10-01. It has received 449 citations till now. The article focuses on the topics: Dysbiosis & Gut flora.

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Citations
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Probiotic Lactobacillus plantarum Promotes Intestinal Barrier Function by Strengthening the Epithelium and Modulating Gut Microbiota

TL;DR: The findings suggest that L. plantarum ZLP001 fortifies the intestinal barrier by strengthening epithelial defense functions and modulating gut microbiota.
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Gastrointestinal tract (gut) health in the young pig

TL;DR: ‘gut health’ represents the outcome of the GIT in response to its capacity and ability to respond and adapt to the insults and challenges it encounters and is of obvious interest in the newly-weaned pig.
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Piglet gut microbial shifts early in life: causes and effects.

TL;DR: The most recent findings on the piglet gut microbiome shifts as influenced by weaning are reviewed, and how these microbiome changes brought about by various factors that have been shown to affect the development of microbiota in piglets are reviewed.
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Dietary l-Tryptophan Supplementation Enhances the Intestinal Mucosal Barrier Function in Weaned Piglets: Implication of Tryptophan-Metabolizing Microbiota

TL;DR: It is suggested that Trp-metabolizing bacteria in the small intestine of weaned pigs primarily mediated the beneficial effects of dietary Trp on its mucosal integrity, health, and function.
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Exploring fish microbial communities to mitigate emerging diseases in aquaculture

TL;DR: New insights in the diversity and functions of the fish bacterial communities elucidated with next-generation sequencing are described and the potential of the microbes to mitigate (re-)emerging diseases in aquaculture is discussed.
References
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Role of the gut microbiota in immunity and inflammatory disease

TL;DR: Understanding the interaction of the microbiota with pathogens and the host might provide new insights into the pathogenesis of disease, as well as novel avenues for preventing and treating intestinal and systemic disorders.
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The healthy human microbiome

TL;DR: Several definitions of a ‘healthy microbiome’ that have emerged are reviewed, the current understanding of the ranges of healthy microbial diversity, and gaps such as the characterization of molecular function and the development of ecological therapies to be addressed in the future are reviewed.
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Microbiota-mediated colonization resistance against intestinal pathogens.

TL;DR: How immune- mediated colonization resistance against antibiotic-resistant intestinal pathogens is influenced by the composition of the commensal microbiota is discussed and recent advances characterizing the ability of different Commensal bacterial families, genera and species to restore colonization resistance to intestinal pathogens in antibiotic-treated hosts are reviewed.
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Repellent activity of essential oils: a review.

TL;DR: Although from an economical point of view synthetic chemicals are still more frequently used as repellents than essential oils, these natural products have the potential to provide efficient, and safer repellent for humans and the environment.
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Horizontal gene transfer: building the web of life.

TL;DR: How HGT has shaped the web of life is described using examples of HGT among prokaryotes, between proKaryotes and eukaryote, and even between multicellular eukaries, to discuss replacement and additive HGT.
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