Heat stress induced Cup9 dependent transcriptional regulation of Sir2
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...was then cross-linked with 1% formaldehyde at 30C for 15 minutes and the experiment was performed as mentioned earlier (Laskar et al., 2014)....
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...It modulates the activity of chromatin modifiers and thereby alters gene expression (Laskar et al., 2011; Laskar et al., 2014; Tariq et al., 2009; Khurana and Bhattacharyya, 2015)....
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"Heat stress induced Cup9 dependent ..." refers background in this paper
...Sir2-mediated telomere silencing plays a major role in mutually exclusive expression of virulent multigene family in protozoan parasites such as Plasmodium and trypanosomes (50, 51)....
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"Heat stress induced Cup9 dependent ..." refers background in this paper
...Sir3 and Sir4 recruit additional Sir2, and thus, the renewal of this cycle causes the spread of the Sir complex along the chromosome (9)....
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