HIF-1–Dependent Stromal Adaptation to Ischemia Mediates In Vivo Tumor Radiation Resistance
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Cites background from "HIF-1–Dependent Stromal Adaptation ..."
...The spatiotemporal dinamic of adaptive response to radiation induced by HIF-1α expression is demonstrated by Schwartz et al (Schwartz et al., 2011)....
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"HIF-1–Dependent Stromal Adaptation ..." refers background in this paper
...Given prosurvival and angiogenic effects of HIF-1, targeted inhibition of HIF-1 signaling has generated interest as a target for therapeutic modulation of radioresistance (5)....
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"HIF-1–Dependent Stromal Adaptation ..." refers methods in this paper
...This initial registration was then further refined through the multiresolution iterative maximization of a normalized mutual information cost function (18)....
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"HIF-1–Dependent Stromal Adaptation ..." refers background in this paper
...Tumor vessels are distinct from their normal counterparts by virtue of their dependence on prosurvival stimulatory cytokines such as VEGF (8)....
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"HIF-1–Dependent Stromal Adaptation ..." refers background in this paper
...HIF-1– stimulated tumor expression of VEGF and other proangiogenic factors is key to this process (27)....
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