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Journal ArticleDOI

High concentration and productivity of 1,3-propanediol from continuous fermentation of glycerol by Klebsiella pneumoniae

K. Menzel, +2 more
- 01 Feb 1997 - 
- Vol. 20, Iss: 2, pp 82-86
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TLDR
In a continuous fermentation of glycerol by Klebsiella pneumoniae, a final propanediol concentration of 35.2–48.5 g l−1 and a volumetric productivity of 4.9-fold higher can be obtained at dilution rates between 0.1 and 0.25 h−1, correspond to about 80–96% of the theoretical maxima under ideal conditions.
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This article is published in Enzyme and Microbial Technology.The article was published on 1997-02-01. It has received 265 citations till now. The article focuses on the topics: Propanediol & Fermentation.

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Citations
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Journal ArticleDOI

Glycerol: A promising and abundant carbon source for industrial microbiology

TL;DR: Glycerol bioconversion in valuable chemicals, such as 1,3-propanediol, dihydroxyacetone, ethanol, succinate etc. is discussed in this review article.
Journal ArticleDOI

Glycerol: Production, consumption, prices, characterization and new trends in combustion

TL;DR: In this paper, an attempt has been made to review the different approaches and techniques used to produce glycerol (hydrolysis, transesterification, refining crude glycerols).
Journal ArticleDOI

Microbial production of 1,3-propanediol.

TL;DR: Great efforts are now being made to combine the pathway from glucose to glycerol successfully with the bacterial route from Glycerol to 1,3-PD, which may become the first bulk chemical produced by a genetically engineered microorganism.
Journal ArticleDOI

Biotechnological production of 2,3-butanediol—Current state and prospects

TL;DR: This review summarizes hitherto gained knowledge and experience in biotechnological production of 2,3-BD, sources of biomass used, employed microorganisms both wild type and genetically improved strains, as well as operating conditions applied.
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Microbial production of 1,3-propanediol: recent developments and emerging opportunities.

TL;DR: Present review gives an overview on 1,3-propanediol production by wild and recombinant strains, and attempts to encompass the various issues concerned in utilization of crude glycerol for 1, 3-pro panediolProduction, with particular emphasis laid on biodiesel industries.
References
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Journal ArticleDOI

Fermentation of glycerol to 1,3-propanediol by Klebsiella and Citrobacter strains

TL;DR: Glycerol-fermenting anaerobes were enriched with glycerol at low and high concentrations in order to obtain strains that produce 1,3-propanediol, and Enterobacterial strains of the genera Enterobacter, Klebsiella, and Citrobacter showed similar product patterns except for one group which formed limited amounts of ethanol, but no propanediol.
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Multiple product inhibition and growth modeling of clostridium butyricum and klebsiella pneumoniae in glycerol fermentation

TL;DR: The inhibition potentials of products and substrate on the growth of Clostridium butyricum and Klebsiella pneumoniae in the glycerol fermentation are examined from experimental data and with a mathematical model.
Journal ArticleDOI

Glycerol conversion to 1,3-propanediol by newly isolated clostridia

TL;DR: The observations point to a substantial transfer of reducing potential from ferredoxin to NAD, which finally results in increased 1,3-propanediol production.
Journal ArticleDOI

Pathway analysis of glycerol fermentation by Klebsiella pneumoniae: Regulation of reducing equivalent balance and product formation

TL;DR: Findings indicate the existence of enzymes in K. pneumoniae that transfer reducing equivalents from NADH2 to H2 and 1,3-propanediol flexibility, and the physiological meanings of these regulatory mechanisms are discussed from the viewpoint of bioenergetics and product inhibition.
Journal ArticleDOI

Fermentative production of 1,3-propanediol from glycerol by Clostridium butyricum up to a scale of 2m 3

TL;DR: The conversion of glycerol to 1,3-propanediol (PD) by Clostridium butyricum DSM 5431 was studied in anaerobic culture and growth and product formation were optimal at pH = 7.0 and T = 35° C, while aeration rate and stirrer speed were found to have no significant influence.
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