Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells.
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...…cell biology, but also in the ability to generate patient-specific iPSC clones, which can then be further differentiated into the cell lineage of choice, including hematopoietic, cardiomyocyte, and hepatocyte cell lineages (Moretti et al., 2010a, 2010b; Raya et al., 2010; Si-Tayeb et al., 2010)....
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...Previous studies have demonstrated the usefulness of iPSCs not only in the study of basic stem cell biology, but also in the ability to generate patient-specific iPSC clones, which can then be further differentiated into the cell lineage of choice, including hematopoietic, cardiomyocyte, and hepatocyte cell lineages (Moretti et al., 2010a, 2010b; Raya et al., 2010; Si-Tayeb et al., 2010)....
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