HIV/SARS-CoV-2 coinfection: A global perspective.
Osman N. Kanwugu,Parise Adadi +1 more
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TLDR
This review seeks to provide a holistic overview of SARS‐CoV‐2 infection in PLWH and controversial suggestion that HIV‐infected individuals could be protected from severe COVID‐19 by means of antiretroviral therapy or HIV‐related immunosuppression.Abstract:
Since its first appearance in Wuhan, China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world and has become a global pandemic. Several medical comorbidities have been identified as risk factors for coronavirus disease 2019 (COVID-19). However, it remains unclear whether people living with human immunodefeciency virus (PLWH) are at an increased risk of COVID-19 and severe disease manifestation, with controversial suggestion that HIV-infected individuals could be protected from severe COVID-19 by means of antiretroviral therapy or HIV-related immunosuppression. Several cases of coinfection with HIV and SARS-CoV-2 have been reported from different parts of the globe. This review seeks to provide a holistic overview of SARS-CoV-2 infection in PLWH.read more
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References
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Journal ArticleDOI
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area.
Safiya Richardson,Safiya Richardson,Jamie S. Hirsch,Jamie S. Hirsch,Mangala Narasimhan,James M. Crawford,Thomas McGinn,Thomas McGinn,Karina W. Davidson,Karina W. Davidson,Douglas P. Barnaby,Douglas P. Barnaby,Lance B Becker,John Chelico,John Chelico,Stuart L. Cohen,Stuart L. Cohen,Jennifer Cookingham,Kevin Coppa,Michael A Diefenbach,Andrew J. Dominello,Joan Duer-Hefele,Louise Falzon,Jordan Gitlin,Negin Hajizadeh,Negin Hajizadeh,Tiffany G. Harvin,David Hirschwerk,Eun Ji Kim,Eun Ji Kim,Zachary Kozel,Lyndonna Marrast,Lyndonna Marrast,Jazmin N. Mogavero,Gabrielle A. Osorio,Michael Qiu,Theodoros P. Zanos +36 more
TL;DR: This case series provides characteristics and early outcomes of sequentially hospitalized patients with confirmed COVID-19 in the New York City area and assesses outcomes during hospitalization, such as invasive mechanical ventilation, kidney replacement therapy, and death.
Journal ArticleDOI
Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China.
TL;DR: This study conducted a retrospective multicenter study of 68 death cases and 82 discharged cases with laboratory-confirmed infection of SARS-CoV-2 and confirmed that some patients died of fulminant myocarditis, which is characterized by a rapid progress and a severe state of illness.
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Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis.
Wei Jie Guan,Wenhua Liang,Yi Zhao,Heng Rui Liang,Zi Sheng Chen,Yimin Li,Xiaoqing Liu,Ru Chong Chen,Chun Li Tang,Tao Wang,Chun-Quan Ou,Li Li,Ping Yan Chen,Ling Sang,Wei Wang,Jianfu Li,Caichen Li,Li Min Ou,Bo Cheng,Shan Xiong,Zheng Yi Ni,Jie Xiang,Yu Hu,Lei Liu,Hong Shan,Chun Liang Lei,Yi Xiang Peng,Li Wei,Yong Liu,Ya Hua Hu,Peng Peng,Jian-ming Wang,Ji Yang Liu,Zhong Chen,Gang Li,Zhi Jian Zheng,Shao Qin Qiu,Jie Luo,Chang Jiang Ye,Shao Yong Zhu,Lin Ling Cheng,Feng Ye,Shi Yue Li,Jin Ping Zheng,Nuo Fu Zhang,Nanshan Zhong,Jianxing He +46 more
TL;DR: It is found that among laboratory confirmed cases of COVID-19, patients with any comorbidity yielded poorer clinical outcomes than those without and a greater number ofComorbidities also correlated with poorer clinical outcome.
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Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study.
Annemarie B Docherty,Ewen M Harrison,Christopher A Green,Hayley E Hardwick,Riinu Pius,Lisa Norman,Karl A Holden,Jonathan M. Read,Frank Dondelinger,Gail Carson,Laura Merson,James A. Lee,Daniel Plotkin,Louise Sigfrid,Sophie Halpin,Clare Jackson,Carrol Gamble,Peter Horby,Jonathan S. Nguyen-Van-Tam,Antonia Ho,Clark D Russell,Jake Dunning,Jake Dunning,Peter J. M. Openshaw,J Kenneth Baillie,Malcolm G Semple +25 more
TL;DR: In study participants, mortality was high, independent risk factors were increasing age, male sex, and chronic comorbidity, including obesity, and the importance of pandemic preparedness and the need to maintain readiness to launch research studies in response to outbreaks is shown.
Journal ArticleDOI
Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China.
Pingzheng Mo,Yuanyuan Xing,Yu Xiao,Liping Deng,Qiu Zhao,Hongling Wang,Yong Xiong,Zhenshun Cheng,Shicheng Gao,Ke Liang,Mingqi Luo,Tielong Chen,Shihui Song,Zhiyong Ma,Xiaoping Chen,Ruiying Zheng,Qian Cao,Fan Wang,Yongxi Zhang +18 more
TL;DR: Wang et al. as mentioned in this paper investigated the characteristics of patients with refractory CoV-2-infected pneumonia (COVID-19) and found that nearly 50% patients could not reach obvious clinical and radiological remission within 10 days after hospitalization.