HIV transmission risk through anal intercourse: systematic review, meta-analysis and implications for HIV prevention
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...A similar pooled estimate [140 per 10 000 exposures, 95% confidence interval (CI) 20–250] was calculated using a random-effects model [6]....
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...First, we established what was already known, starting with a series of recent systematic reviews and metaanalyses that were identified through a comprehensive literature review conducted for a related project that also examined per-act HIV transmission risk and provided estimates of pooled per-act HIV transmission probabilities for blood transfusion [5], parenteral exposures [5], receptive anal intercourse [6], receptive penile–vaginal intercourse [7], insertive penile–vaginal intercourse [7], and mother-to-child transmission [8]....
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...Summary of HIV transmission risk estimates The estimated per-act HIV transmission risk (all expressed as per 10 000 exposures) was greatest for blood transfusion [9250 (95% CI 8900–9610)], followed by mother-to-child transmission [2260 (95% CI 1700–2900)], receptive anal intercourse [138 (95% CI 102–186)], needle-sharing injection drug use [63 (95% CI 41–92)], and percutaneous needle stick injuries [23 (95% CI 0–46)] [5,6,8,10]....
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...A 2010 meta-analysis [6] provided an estimate of this risk based on data from...
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Cites background from "HIV transmission risk through anal ..."
...[44] have reported, is the very high transmission efficiency of receptive anal intercourse – at an estimated 1....
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