HIV Treatment as Prevention: Issues in Economic Evaluation
Citations
67 citations
Cites background from "HIV Treatment as Prevention: Issues..."
...For example, the probability that a person who is currently eligible for ART will initiate ART is the same as the probability that a person who is currently eligible will have once she has reached ART eligibility; this assumption may not hold in many contexts, for example, when the composition of people presenting to ART programs changes because over time the proportion of ‘early adopters’ is decreasing, whereas the proportion of ‘laggards’ is increasing, or because changing ART guidelines attract different populations to engage in HIV care [38]....
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66 citations
Cites background from "HIV Treatment as Prevention: Issues..."
...A second paper focussing on economic evaluation in this collection further discusses how operational and effectiveness issues in scaling up ART for prevention will affect its cost-effectiveness [10]....
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...N Another article in this PLoS Medicine collection [10] discusses additional operational and effectiveness issues relevant for the economic evaluation of scaling up ART for prevention....
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...Our view that programme characteristics such as scale/ coverage, scope, managerial incentives, and quality/effectiveness can have important effects on the costs of ART delivery is endorsed by a second paper in this PLoS Medicine collection [10], which also points to the difficulty of projecting the future costs of technologies that are not yet widely used or have not even been invented....
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63 citations
57 citations
Cites background from "HIV Treatment as Prevention: Issues..."
...Evidence from recent systematic reviews have found high rates of patient attrition along the cascade of care, from testing to treatment [37,38], and although recent efforts have been made to identify strategies to improve linkage to care [39 & ], adherence to treatment [40], and retention in care [41], much more remains to be done....
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55 citations
References
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"HIV Treatment as Prevention: Issues..." refers result in this paper
...The results from the HTPN 052 trial reported in August 2011 demonstrated under the controlled conditions of a well-conducted clinical trial that early antiretroviral therapy (ART) can be highly effective in preventing transmission of HIV in stable heterosexual HIV-discordant couples [1]....
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1,948 citations
"HIV Treatment as Prevention: Issues..." refers background in this paper
...Of course, the specific components required for successful TasP will depend on the particular TasP intervention strategy—universal population-wide HIV testing and treatment will use different approaches, and incur different costs, than TasP strategies targeted at people at high risk of HIV transmission, such as HIV-infected individuals in HIV-discordant couples [2,13,20]....
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...[13] assert based on their modeling results, the economic case for TasP would likely be robust to large increases in the cost estimates....
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...[13], it may not alter the overall conclusion that TasP is a socially worthwhile intervention....
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...[13] ‘‘for scale and a plausible pattern of distribution of patients into clinics’’ [8]....
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361 citations
Additional excerpts
...A few mathematical modeling studies have predicted the cost-effectiveness of TasP, using cost estimates derived from currently existing ART programs [4–7]....
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