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Journal ArticleDOI

How Bacteria Stick

J. W. Costerton, +2 more
- 01 Jan 1978 - 
- Vol. 238, Iss: 1, pp 86-95
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This article is published in Scientific American.The article was published on 1978-01-01. It has received 1425 citations till now. The article focuses on the topics: Bacterial Physiological Phenomena & Bacteria.

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Bacterial biofilms : A common cause of persistent infections

TL;DR: Improvements in understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.
Journal ArticleDOI

Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms

TL;DR: It is understood that biofilms are universal, occurring in aquatic and industrial water systems as well as a large number of environments and medical devices relevant for public health, and that treatments may be based on inhibition of genes involved in cell attachment and biofilm formation.
Journal ArticleDOI

Biofilms: microbial life on surfaces.

TL;DR: A greater understanding of biofilm processes should lead to novel, effective control strategies for biofilm control and a resulting improvement in patient management.
Journal ArticleDOI

Biofilms as complex differentiated communities.

TL;DR: It is submitted that complex cell-cell interactions within prokaryotic communities are an ancient characteristic, the development of which was facilitated by the localization of cells at surfaces, which may have provided the protective niche in which attached cells could create a localized homeostatic environment.
Journal ArticleDOI

Biomaterial-centered infection: microbial adhesion versus tissue integration.

TL;DR: Modifications to biomaterial surfaces at an atomic level will allow the programming of cell-to-substratum events, thereby diminishing infection by enhancing tissue compatibility or integration, or by directly inhibiting bacterial adhesion.
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