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Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems.

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TLDR
A causal relationship between the reproductive disorders and exposure to specific toxicants is yet to be established, due to the complexity of the clinical protocols used, the degree of occupational or environmental exposure, the determination of the variables measured and the sample size of the subjects examined.
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This article is published in Environmental Toxicology and Pharmacology.The article was published on 2017-04-01. It has received 273 citations till now. The article focuses on the topics: Environmental exposure.

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Citations
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Fertility and infertility: Definition and epidemiology.

TL;DR: The chance of becoming spontaneously pregnant declines with the duration before conception, and the three major factors influencing the spontaneous probability of conception are the time of unwanted non-conception, the age of the female partner and the disease-related infertility.
Journal ArticleDOI

Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention.

TL;DR: In this article, a review of potential EDCs, their effects and mechanisms of action, epidemiological studies to analyze their effects on human health, bio-detection and chemical identification methods, difficulties in extrapolating experimental findings and studying endocrine disruptors in humans and recommendations for endocrinologists, individuals and policy makers will be discussed in view of the relevant literature.
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Emergent contaminants: Endocrine disruptors and their laccase-assisted degradation - A review.

TL;DR: Information is presented on how laccase-assisted approach can change this limited tendency of physical and chemical based approaches to tackle emerging contaminants at large and endocrine disruptor removal.
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Recent developments in physical, biological, chemical, and hybrid treatment techniques for removing emerging contaminants from wastewater.

TL;DR: The state-of-art technologies used to remove ECs from wastewater through a comprehensive review are presented and a hybrid technique of ozonation accompanied by activated carbon was found significantly effective in removing some ECs, particularly pharmaceuticals and pesticides.
References
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Journal ArticleDOI

Evidence for decreasing quality of semen during past 50 years.

TL;DR: There has been a genuine decline in semen quality over the past 50 years, and as male fertility is to some extent correlated with sperm count the results may reflect an overall reduction in male fertility.
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Environmental epigenomics and disease susceptibility.

TL;DR: An increasing body of evidence from animal studies supports the role of environmental epigenetics in disease susceptibility and recent studies have demonstrated for the first time that heritable environmentally induced epigenetic modifications underlie reversible transgenerational alterations in phenotype.
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Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist.

TL;DR: It is reported that the major and persistent DDT metabolite,P,P′-DDE (l,l-dichloro-2,2-bis(P- chlorophenyl)ethylene), has little ability to bind the oestrogen receptor, but inhibits androgen binding to the androgen receptor.
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Bisphenol A and human health: a review of the literature.

TL;DR: The growing human literature correlating environmental BPA exposure to adverse effects in humans, along with laboratory studies in many species including primates, provides increasing support that environmental B PA exposure can be harmful to humans, especially in regards to behavioral and other effects in children.
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Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood

TL;DR: There is considerable evidence to indicate that disorders of maturation of Sertoli cells may be a common underlying cause of human male reproductive disorders that manifest at various life stages.
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