Human rabies: neuropathogenesis, diagnosis, and management
Citations
372 citations
291 citations
Cites background from "Human rabies: neuropathogenesis, di..."
...How this dysfunction is linked to the disease manifestations (both furious and paralytic) is not completely understood [89]....
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211 citations
Cites background from "Human rabies: neuropathogenesis, di..."
...Small DRG neurons that target higher order interneurons in the dorsal horn are subsequently infected [54], eventually leading to infection of the brain stem and the limbic system....
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...Bat-associated RABV infection usually presents with myoclonus, hemichorea and symptoms related to a one-side deficiency of the sympathetic trunk activity, such as a weak, droopy eyelid, constricted pupil, decreased sweating and in some cases an inset eyeball [54, 130]....
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156 citations
Cites background from "Human rabies: neuropathogenesis, di..."
...However, in resource-challenged environments with poor case detection or lack of affordable access to postexposure prophylaxis, untreated rabies results in eventual paralysis, coma, end-organ damage, and death in nearly all cases (7, 204, 205)....
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153 citations
References
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