Human skin: source of and target organ for angiotensin II.
Citations
534 citations
402 citations
Cites background from "Human skin: source of and target or..."
...Recent research has demonstrated that angiotensin receptors are expressed in human skin and that tissue renin–angiotensin system plays an important role in the wound healing process [82, 83]....
[...]
259 citations
164 citations
144 citations
Cites background from "Human skin: source of and target or..."
...These adverse effects may be caused by the suppression or blockade of normal Ang II-mediated physiological functions in target organ systems [2, 38, 39] thereby creating a need for an alternative approach to selective targeting of the Ang II-mediated detrimental effects in the heart....
[...]
References
917 citations
823 citations
"Human skin: source of and target or..." refers background in this paper
...antagonists (losartan for AT1 receptors and PD 123319 for AT2 receptors) (14,15)....
[...]
767 citations
"Human skin: source of and target or..." refers background in this paper
...antagonists (losartan for AT1 receptors and PD 123319 for AT2 receptors) (14,15)....
[...]
701 citations
"Human skin: source of and target or..." refers background in this paper
...AT1 receptors mediate the stimulation of proliferation in diverse cell types (8,31,32)....
[...]
...The AT2 receptor turned out to be involved in proliferation control (5,7,8), cell differentiation (5,9,10), apoptosis (6), tissue repair and tissue remodelling (11,12)....
[...]
596 citations