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Hydroxyapatite nano bioceramics optimized 3D printed poly lactic acid scaffold for bone tissue engineering application

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TLDR
In this paper, the effects of 3D-printing at different orientations on the mechanical properties of synthesized 3Dpolylactic acid (PLA) and hydroxyapatite-modified PLA (PLA-HAp) scaffolds were examined.
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This article is published in Ceramics International.The article was published on 2020-02-15. It has received 108 citations till now.

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Recent advances in 3D-printed polylactide and polycaprolactone-based biomaterials for tissue engineering applications.

TL;DR: In this paper , the recent advancements in the PLA and PCL biodegradable polymer-based composites as well as their reinforcement with hydrogels and bio-ceramics scaffolds manufactured through 3DP are systematically summarized and the applications of bone, cardiac, neural, vascularized and skin tissue regeneration are thoroughly elucidated.
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Biopolymeric Sustainable Materials and their Emerging Applications

TL;DR: An overview of the latest knowledge of different natural and synthetic-based biodegradable polymers and their fiber-reinforced composites is presented in this paper , which discusses different degradation mechanisms of biopolymer-based composites as well as their sustainability aspects.
Journal ArticleDOI

Synthesis and Characterization of PLA-Micro-structured Hydroxyapatite Composite Films

TL;DR: A facile synthesis method used to obtain new composite films based on polylactic acid and micro-structured hydroxyapatite particles, with a significant decrease in the crystallinity compared to the pure polymer.
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Bioactive polymeric scaffolds for osteogenic repair and bone regenerative medicine.

TL;DR: This review provides comprehensive insights into different synthetic and natural polymers used for the regeneration of bone tissue and discusses various technologies applied for the engineering of BPSs and their physicomechanical properties and biological effects.
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3D Printing and Nanotechnology: A Multiscale Alliance in Personalized Medicine

TL;DR: An extensive review about scientific studies that ally 3D printing and nanomaterials in the development of new approaches for pharmaceutical and medical applications for the treatment and prevention of diseases is presented here.
References
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Journal ArticleDOI

Bone substitutes in orthopaedic surgery: from basic science to clinical practice

TL;DR: The alternative available techniques used for bone fusion are reviewed and update, along with some hints on the advancements achieved through the experimental research in this field.
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Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering.

TL;DR: Results show that the biodegradable polymer/bioceramic composite scaffolds fabricated by the novel GF/PL method enhance bone regeneration compared with those fabricated byThe conventional SC/PL methods.
Journal ArticleDOI

Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering

TL;DR: A new process chain for custom-made three-dimensional (3D) porous ceramic scaffolds for bone replacement with fully interconnected channel network for the repair of osseous defects from trauma or disease is reported.
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Surface modification and property analysis of biomedical polymers used for tissue engineering.

TL;DR: Current techniques and their developments to measure cell adhesion, proliferation, morphology, viability, migration, migration and gene expression are reviewed.
Journal ArticleDOI

Nano-composite of poly(L-lactide) and surface grafted hydroxyapatite: mechanical properties and biocompatibility.

TL;DR: The results of biocompatibility test showed that the g-HAP existing in the PLLA composite facilitated both adhesion and proliferation of chondrocytes on the P LLA/g-H AP composite film, implying that PLLa could be strengthened as well as toughened by g- HAP nano-particles.
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