Hyperpolarized 129Xe MRI of the human lung
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"Hyperpolarized 129Xe MRI of the hum..." refers methods in this paper
...Although the first hyperpolarized-gas MR images were obtained using hyperpolarized (129)Xe (11), and images of the human lung were acquired with hyperpolarized (129)Xe only a few years later (12), the vast majority of work in humans has been performed using hyperpolarized (3)He instead....
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"Hyperpolarized 129Xe MRI of the hum..." refers background in this paper
...In the second step of OPSE, collisions between spin-polarized rubidium atoms and noble-gas (129Xe or 3He) atoms within the cell result in spin exchange—the transfer of polarization from rubidium electrons to noble-gas nuclei (Fig....
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...Nonetheless, the nuclear polarization can be increased dramatically compared to that produced by the magnet of the MR scanner by using a method called optical pumping and spin exchange (OPSE) (9,38), which was originally developed for nuclear-physics experiments many years before being applied to medical imaging....
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...While the basic OPSE process described above is effective for generating high polarization in a ‘‘batch’’ of pressurized 3He over a period of several hours, the situation is somewhat more complicated for 129Xe....
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...As its name implies, OPSE is, in concept, a twostep process....
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...cal pumping and spin exchange (OPSE) (9,38), which was originally developed for nuclear-physics experi-...
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