Hyperthermic effects of dissipative structures of magnetic nanoparticles in large alternating magnetic fields
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TLDR
Numerically compared the magnetic loss in rotatable nanoparticles in aqueous media with that of non-rotatable nanoparticle anchored to localised structures to shed new light on the design of targeted magnetic hyperthermia treatments.Abstract:
Targeted hyperthermia treatment using magnetic nanoparticles is a promising cancer therapy. However, the mechanisms of heat dissipation in the large alternating magnetic field used during such treatment have not been clarified. In this study, we numerically compared the magnetic loss in rotatable nanoparticles in aqueous media with that of non-rotatable nanoparticles anchored to localised structures. In the former, the relaxation loss in superparamagnetic nanoparticles has a secondary maximum because of slow rotation of the magnetic easy axis of each nanoparticle in the large field in addition to the known primary maximum caused by rapid Neel relaxation. Irradiation of rotatable ferromagnetic nanoparticles with a high-frequency axial field generates structures oriented in a longitudinal or planar direction irrespective of the free energy. Consequently, these dissipative structures significantly affect the conditions for maximum hysteresis loss. These findings shed new light on the design of targeted magnetic hyperthermia treatments.read more
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Fundamentals and advances in magnetic hyperthermia
Elio Alberto Perigo,Gauvin Hemery,Olivier Sandre,Daniel Ortega,Daniel Ortega,Daniel Ortega,Eneko Garaio,Fernando Plazaola,Francisco J. Teran,Francisco J. Teran +9 more
TL;DR: A broad overview of magnetic hyperthermia addressing new perspectives and the progress on relevant features such as the ad hoc preparation of magnetic nanoparticles, physical modeling of magnetic heating, methods to determine the heat dissipation power of magnetic colloids including the development of experimental apparatus and the influence of biological matrices on the heating efficiency is presented in this article.
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Magnetic Properties of Magnetic Nanoparticles for Efficient Hyperthermia.
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Physics of heat generation using magnetic nanoparticles for hyperthermia
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