Identification and Characterization of the Capsular Polysaccharide (K-Antigen) Locus of Porphyromonas gingivalis
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Cites background from "Identification and Characterization..."
...The CPS of P. gingivalis A major virulence factor of P. gingivalis is considered to be its capsule, also known as CPS or K-antigen (Schifferle et al., 1989; Holt et al., 1999; Farquharson et al., 2000; Aduse-Opoku et al., 2006; Brunner et al., 2010a, b)....
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Cites background from "Identification and Characterization..."
...The antibody mAb 1B5 recognizes a Mana1-2Mana1-phosphate side chain in anionic polysaccharides but not lipopolysaccharides (LPS; O antigen attached to lipid A core) or capsular polysaccharides [12,13]....
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...gingivalis produces at least three polysaccharide molecules on its surface: O-LPS (O antigen attached to a lipid A core) [20], ALPS (phosphorylated branched mannan repeat units attached to a lipid A core) [14] and capsular polysaccharides [13]....
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126 citations
Cites background from "Identification and Characterization..."
...Recently, the sequence surrounding PG0106 in wild-type strain 381 was submitted to NCBI (accession number AJ969093) (2)....
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References
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"Identification and Characterization..." refers methods in this paper
...electrophoresis (SDS-PAGE) was performed in 10% polyacrylamide gels (26)....
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"Identification and Characterization..." refers background in this paper
...Arg- and Lys-gingipains in spent culture medium were fluorescently labeled with DNS-EGR-CK, subjected to SDS-PAGE, and viewed under UV light....
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...Factors of P. gingivalis considered to be of importance in the pathogenesis of periodontal disease include the major cell surface macromolecules, capsular polysaccharide (CPS) (or K-antigen) and lipopolysaccharide (LPS), and the extracellular/surface cysteine proteases, the Arg- and Lys-gingipains (30)....
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...gingivalis considered to be of importance in the pathogenesis of periodontal disease include the major cell surface macromolecules, capsular polysaccharide (CPS) (or K-antigen) and lipopolysaccharide (LPS), and the extracellular/surface cysteine proteases, the Arg- and Lys-gingipains (30)....
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