Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
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...1 ), but it is more distant from SARS-CoV (~79% similarity) and Middle East respiratory syndrome coronavirus (MERS-CoV) (~50% similarity) [23 , 25 , 26] ....
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Cites background from "Identification of a novel coronavir..."
...9%, suggesting a very recent host shift into humans [1-3]....
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1,350 citations
Cites background or methods from "Identification of a novel coronavir..."
...A novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease in 2019 (COVID-19) emerged as a major pandemic [1, 2]....
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...Among them, 43 (20 severe and 23 mild to moderate) were confirmed virus positive (referred as “confirmed cases” [CCs]) by deep sequencing or a qPCR assay with a detection limit of 1 copy/μL, as previously reported [1, 2], while 58 cases (5 severe and 53 mild to moderate) suspected to be infected with SARS-CoV-2 based on clinical manifestation, chest radiography imaging, and epidemiology but no virus were detected by deep sequencing or a qPCR assay (referred as “probable cases” [PCs])....
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References
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"Identification of a novel coronavir..." refers background in this paper
...Sequence homology analysis of the viral genome showed that the CoV identified in this study is distinct from any of the known human CoVs, including SARS-CoV and MERS-CoV....
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...Since the beginning of this century, two zoonotic CoVs, SARSCoV and MERS-CoV, have been identified to cause severe human diseases.([3,4,7]) The outbreak of SARS-CoV in 2003 was responsible for 8096 cases and 774 deaths worldwide....
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...The phylogenetic trees constructed with the sequences of the RdRp, S, and N genes, and the whole genome using a maximum-likelihood model showed that all five novel CoVs were closely related to bat SL-CoVs ZXC21 and ZC45, but in a separate evolutionary lineage under the 1 ORF3 and intact ORF8 gene regions were present in the novel CoVs, which are the characteristic features of batorigin CoVs....
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...[5,6] Since the beginning of this century, two zoonotic CoVs, SARSCoV and MERS-CoV, have been identified to cause severe human diseases....
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...Clarification of the coronavirome in animals, particularly in bats as a key reservoir of a wide range of CoVs, should be a priority for any task force....
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2,794 citations
"Identification of a novel coronavir..." refers background in this paper
...Since the beginning of this century, two zoonotic CoVs, SARSCoV and MERS-CoV, have been identified to cause severe human diseases.([3,4,7]) The outbreak of SARS-CoV in 2003 was responsible for 8096 cases and 794 deaths worldwide....
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