Journal ArticleDOI
IgG4-related disease: a clinical perspective.
Reads0
Chats0
TLDR
The first-line treatment of IgG4-RD is based on glucocorticoids, which are usually efficacious, but B cell depletion induced by rituximab has also been found to induce remission in steroid-resistant disease or has been used as steroid-sparing agent for relapsing disease.Citations
More filters
Journal ArticleDOI
A Glance at the Use of Glucocorticoids in Rare Inflammatory and Autoimmune Diseases: Still an Indispensable Pharmacological Tool?
Simona Ronchetti,Emira Ayroldi,Erika Ricci,Marco Gentili,Graziella Migliorati,Carlo Riccardi +5 more
TL;DR: In this paper, the authors focus on rare autoimmune and chronic inflammatory diseases for which the biomedical research investment in new therapies is less likely, and critically evaluate the possibility of treating such diseases with other drugs, either glucocorticoid-related or unrelated.
Journal ArticleDOI
A Systematic Review and Meta-Analysis of Immunoglobulin G Abnormalities and the Therapeutic Use of Intravenous Immunoglobulins (IVIG) in Autism Spectrum Disorder.
TL;DR: A systematic review and meta-analysis examined the studies which assessed immunoglobulin G (IgG) concentrations and the therapeutic use of IVIG for individuals with ASD as discussed by the authors.
Journal ArticleDOI
The enigmatic immunoglobulin G4-related disease and its varied cardiovascular manifestations.
TL;DR: In this paper, the authors provide a review of the published literature on cardiovascular manifestations of immunoglobulin G4-related disease and provide a basis for diagnosis and management of the condition by the practising cardiologist.
Journal ArticleDOI
Eosinophilic granulomatosis with polyangiitis: A review.
White Jpe,Satya Dev Dubey +1 more
TL;DR: In this article , the authors discuss the pathophysiology, clinical features and diagnosis, management and prognosis of Eosinophilic granulomatosis with polyangiitis (EGPA), a rare, multi-system, inflammatory disease, belonging to the group of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV).
Journal ArticleDOI
Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease
Xunyao Wu,Yu Peng,Jieqiong Li,Panpan Zhang,Zheng Liu,Hui Lu,Linyi Peng,Jiaxin Zhou,Yunyun Fei,Xiaofeng Zeng,Yan Zhao,Wen Zhang +11 more
TL;DR: This study enhances the understanding of the cellular heterogeneity and transcriptional features involved in the pathogenesis of IgG4-RD, providing key clinical implications.
References
More filters
Journal ArticleDOI
High serum IgG4 concentrations in patients with sclerosing pancreatitis.
Hideaki Hamano,Shigeyuki Kawa,Akira Horiuchi,Hiroshi Unno,Naoyuki Furuya,Taiji Akamatsu,Mana Fukushima,Toshio Nikaido,Kohzo Nakayama,Nobuteru Usuda,Kendo Kiyosawa +10 more
TL;DR: Patients with sclerosing pancreatitis have high serum IgG4 concentrations, providing a useful means of distinguishing this disorder from other diseases of the pancreas or biliary tract.
Journal ArticleDOI
Consensus statement on the pathology of IgG4-related disease
Vikram Deshpande,Yoh Zen,John Kc Chan,Eunhee E Yi,Yasuharu Sato,Tadashi Yoshino,Günter Klöppel,J. Godfrey Heathcote,Arezou Khosroshahi,Judith A. Ferry,Rob C. Aalberse,Daniel Bloch,William R. Brugge,Adrian C Bateman,Mollie N. Carruthers,Suresh T. Chari,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,David G. Forcione,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Gregory Y. Lauwers,Yasufumi Masaki,Yasuni Nakanuma,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Thomas C. Smyrk,James Robert Stone,Masayuki Takahira,George Webster,Motohisa Yamamoto,Giuseppe Zamboni,Hisanori Umehara,John H. Stone +40 more
TL;DR: This statement proposes a terminology scheme for the diagnosis of IgG4-related disease that is based primarily on the morphological appearance on biopsy, and advocates the use of strict criteria for accepting newly proposed entities or sites as components of the IgG 4- related disease spectrum.
Journal ArticleDOI
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Hisanori Umehara,Kazuichi Okazaki,Yasufumi Masaki,Mitsuhiro Kawano,Motohisa Yamamoto,Takako Saeki,Shoko Matsui,Tadashi Yoshino,Shigeo Nakamura,Shigeyuki Kawa,Hideaki Hamano,Terumi Kamisawa,Toru Shimosegawa,Akira Shimatsu,Seiji Nakamura,Tetsuhide Ito,Kenji Notohara,Takayuki Sumida,Yoshiya Tanaka,Tsuneyo Mimori,Tsutomu Chiba,Michiaki Mishima,Toshifumi Hibi,Hirohito Tsubouchi,Kazuo Inui,Hirotaka Ohara +25 more
TL;DR: The comprehensive diagnostic criteria for IgG4-RD are practically useful for general physicians and nonspecialists and have increased the sensitivity of diagnosis to 100% for Igg4-related MD, KD, and AIP.
Journal ArticleDOI
IgG4-related disease.
Related Papers (5)
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Hisanori Umehara,Kazuichi Okazaki,Yasufumi Masaki,Mitsuhiro Kawano,Motohisa Yamamoto,Takako Saeki,Shoko Matsui,Tadashi Yoshino,Shigeo Nakamura,Shigeyuki Kawa,Hideaki Hamano,Terumi Kamisawa,Toru Shimosegawa,Akira Shimatsu,Seiji Nakamura,Tetsuhide Ito,Kenji Notohara,Takayuki Sumida,Yoshiya Tanaka,Tsuneyo Mimori,Tsutomu Chiba,Michiaki Mishima,Toshifumi Hibi,Hirohito Tsubouchi,Kazuo Inui,Hirotaka Ohara +25 more
The 2019 American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-related disease
Zachary S. Wallace,Ray Naden,Suresh T. Chari,Hyon K. Choi,Emanuel Della-Torre,Jean Francois Dicaire,Phillip A. Hart,Dai Inoue,Mitsuhiro Kawano,Arezou Khosroshahi,Marco Lanzillotta,Kazuichi Okazaki,Cory A. Perugino,Amita Sharma,Takako Saeki,Nicolas Schleinitz,Naoki Takahashi,Hisanori Umehara,Yoh Zen,John H. Stone +19 more