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Proceedings Article

Image Processing

01 Jan 1994-
TL;DR: The main focus in MUCKE is on cleaning large scale Web image corpora and on proposing image representations which are closer to the human interpretation of images.
Abstract: MUCKE aims to mine a large volume of images, to structure them conceptually and to use this conceptual structuring in order to improve large-scale image retrieval. The last decade witnessed important progress concerning low-level image representations. However, there are a number problems which need to be solved in order to unleash the full potential of image mining in applications. The central problem with low-level representations is the mismatch between them and the human interpretation of image content. This problem can be instantiated, for instance, by the incapability of existing descriptors to capture spatial relationships between the concepts represented or by their incapability to convey an explanation of why two images are similar in a content-based image retrieval framework. We start by assessing existing local descriptors for image classification and by proposing to use co-occurrence matrices to better capture spatial relationships in images. The main focus in MUCKE is on cleaning large scale Web image corpora and on proposing image representations which are closer to the human interpretation of images. Consequently, we introduce methods which tackle these two problems and compare results to state of the art methods. Note: some aspects of this deliverable are withheld at this time as they are pending review. Please contact the authors for a preview.
Citations
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Journal ArticleDOI
TL;DR: The use of the multiscale generalized radial basis function (MSRBF) neural networks for image feature extraction and medical image analysis and classification is proposed for the first time and it is found that the MSRBF networks are able to build tailored and precise image models and, combined with the DCT, to extract high-quality features from both black and white and coloured images.
Abstract: The use of the multiscale generalized radial basis function (MSRBF) neural networks for image feature extraction and medical image analysis and classification is proposed for the first time in this work. The MSRBF networks hold a simple and flexible architecture that has been successfully used in forecasting and model structure detection of input-output nonlinear systems. In this work instead, MSRBF networks are part of an integrated computer-aided diagnosis (CAD) framework for breast cancer detection, which holds three stages: an input-output model is obtained from the image, followed by a high-level image feature extraction from the model and a classification module aimed at predicting breast cancer. In the first stage, the image data is rendered into a multiple-input-single-output (MISO) system. In order to improve the characterisation, the nonlinear autoregressive with exogenous inputs (NARX) model is introduced to rearrange the available input-output data in a nonlinear way. The forward regression orthogonal least squares (FROLS) algorithm is then used to take advantage of the previous arrangement by solving the system as a model structure detection problem and finding the output layer weights of the NARX-MSRBF network. In the second stage, once the network model is available, the feature extraction takes place by stimulating the input to produce output signals to be compressed by the discrete cosine transform (DCT). In the third stage, we leverage the extracted features by using a clustering algorithm for classification to integrate a CAD system for breast cancer detection. To test the method performance, three different and well-known public image repositories were used: the mini-MIAS and the MMSD for mammography, and the BreaKHis for histopathology images. A comparison exercise was also made between different database partitions to understand the mammogram breast density effect in the performance since there are few remarks in the literature on this factor. Classification results show that the new CAD method reached an accuracy of 93.5% in mini-Mammo graphic image analysis society (mini-MIAS), 93.99% in digital database for screening mammography (DDSM) and 86.7% in the BreaKHis. We found that the MSRBF networks are able to build tailored and precise image models and, combined with the DCT, to extract high-quality features from both black and white and coloured images.

13 citations


Cites background from "Image Processing"

  • ...RBF networks are efficient at solving nonlinear system identification problems in spite they hold a linearly weighted structure that eases the training and discards complex nonlinear procedures in the solution algorithm[7, 8]....

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Journal ArticleDOI
TL;DR: The underlying mechanisms of the brain-heart interaction are shown and offer the first evidence that DHI targets the adrenergic pathway to modulate cardiac function in the setting of brain–heart syndrome.
Abstract: Ischemic brain injury impacts cardiac dysfunction depending on the part of the brain affected, with a manifestation of irregular blood pressure, arrhythmia, and heart failure. Generally called brain-heart syndrome in traditional Chinese medicine, few mechanistic understanding and treatment options are available at present. We hypothesize that considering the established efficacy for both ischemic stroke and myocardial infarction (MI), Danhong injection (DHI), a multicomponent Chinese patent medicine, may have a dual pharmacological potential for treating the brain-heart syndrome caused by cerebral ischemic stroke through its multi-targeted mechanisms. We investigated the role of DHI in the setting of brain-heart syndrome and determined the mechanism by which it regulates this process. We induced Ischemia/Reperfusion in Wistar rats and administered intravenous dose of DHI twice daily for 14 days. We assessed the neurological state, infarct volume, CT scan, arterial blood pressure, heart rhythm, and the hemodynamics. We harvested the brain and heart tissues for immunohistochemistry and western blot analyses. Our data show that DHI exerts potent anti-stroke effects (infarct volume reduction: ∗∗p < 0.01 and ∗∗∗p < 0.001 vs. vehicle. Neurological deficit correction: ∗p < 0.05 and ∗∗∗p < 0.001 vs. vehicle), and effectively reversed the abnormal arterial pressure (∗p < 0.05 vs. vehicle) and heart rhythm (∗∗p < 0.01 vs. vehicle). The phenotype of this brain-heart syndrome is strikingly similar to those of MI model. Quantitative assessment of hemodynamic in cardiac functionality revealed a positive uniformity in the PV-loop after administration with DHI and valsartan in the latter. Immunohistochemistry and western blot results showed the inhibitory effect of DHI on the β-adrenergic pathway as well as protein kinase C epsilon (PKCe) (∗∗p < 0.01 vs. model). Our data showed the underlying mechanisms of the brain-heart interaction and offer the first evidence that DHI targets the adrenergic pathway to modulate cardiac function in the setting of brain-heart syndrome. This study has made a novel discovery for proper application of the multi-target DHI and could serve as a therapeutic option in the setting of brain-heart syndrome.

13 citations

Proceedings ArticleDOI
14 Apr 2014
TL;DR: A new approach called hybrid segmentation inspired by both mathematical morphology operators and morphological watershed segmentation is presented, which improves significantly the segmentation and the extraction of the tumor zone.
Abstract: Nowadays, medical image processing and particularly MRI images is the one of the most challenging field and emerging to help specialists in their diagnostics. In this context and to detect automatically suspicious regions or tumors, this paper presents a new approach called hybrid segmentation inspired by both mathematical morphology operators and morphological watershed segmentation. Our approach's advantage comes from the complementarity between these two approaches. The morphological operators extract roughly the tumor region and eventually can affect healthy structures while the watershed method provides details of various brain's structures and therefore the fusion of these two approaches improves significantly the segmentation and the extraction of the tumor zone.

13 citations


Cites methods from "Image Processing"

  • ...Histogram thresholding and slicing techniques are widely used to segment the image[32], [33]....

    [...]

Journal ArticleDOI
TL;DR: Findings support the use of anti-IL-5/il-5R mABs in asthmatics of different age ranges, and age does not significantly affect the efficacy.

13 citations

Journal ArticleDOI
TL;DR: Conjoined epithelial PAR-2 is significantly upregulated in SAC, supporting the view that disruption of the barrier properties of the conjunctival epithelium is an important event in Sac pathogenesis.
Abstract: Aims Aeroallergen exposure to the conjunctival epithelium in seasonal allergic conjunctivitis (SAC) may induce a cellular stress response that disrupts the barrier properties of the conjunctival epithelium, resulting in allergic disease. Whether such changes occur in SAC is unknown. Epithelial permeability is known to be increased when protease activated receptor 2 (PAR-2) is activated. We evaluated the expression of PAR-2 in patients with SAC-in-season (SACS) and compared it with control non-atopic subjects or those with out-of-season allergic conjunctivitis (OSAC). Methods Six SACS, eight normal and four OSAC specimens were examined immunohistochemically for PAR-2 and quantified in a masked fashion for the percentage of epithelia stained for each marker using Image-J software. Conjunctival epithelial heights were measured in all groups to confirm the presence of allergic eye disease. Results Mean percentage staining of PAR-2 was significantly greater in SACS that in normal specimens (73.4±15.4% vs 32.8±30.0%, p=0.038) or in OSAC (73.4±15.4% vs 1.4±2.2%, p=0.01). Mean conjunctival epithelial height was significantly raised in SACS (63.8±9.0 μm) versus controls (44.7±11.2 μm) (p=0.003, unpaired t test). Conclusions Conjunctival epithelial PAR-2 is significantly upregulated in SAC. This supports the view that disruption of the barrier properties of the conjunctival epithelium is an important event in SAC pathogenesis.

13 citations

References
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Journal ArticleDOI
01 Nov 1973
TL;DR: These results indicate that the easily computable textural features based on gray-tone spatial dependancies probably have a general applicability for a wide variety of image-classification applications.
Abstract: Texture is one of the important characteristics used in identifying objects or regions of interest in an image, whether the image be a photomicrograph, an aerial photograph, or a satellite image. This paper describes some easily computable textural features based on gray-tone spatial dependancies, and illustrates their application in category-identification tasks of three different kinds of image data: photomicrographs of five kinds of sandstones, 1:20 000 panchromatic aerial photographs of eight land-use categories, and Earth Resources Technology Satellite (ERTS) multispecial imagery containing seven land-use categories. We use two kinds of decision rules: one for which the decision regions are convex polyhedra (a piecewise linear decision rule), and one for which the decision regions are rectangular parallelpipeds (a min-max decision rule). In each experiment the data set was divided into two parts, a training set and a test set. Test set identification accuracy is 89 percent for the photomicrographs, 82 percent for the aerial photographic imagery, and 83 percent for the satellite imagery. These results indicate that the easily computable textural features probably have a general applicability for a wide variety of image-classification applications.

20,442 citations

Book
03 Oct 1988
TL;DR: This chapter discusses two Dimensional Systems and Mathematical Preliminaries and their applications in Image Analysis and Computer Vision, as well as image reconstruction from Projections and image enhancement.
Abstract: Introduction. 1. Two Dimensional Systems and Mathematical Preliminaries. 2. Image Perception. 3. Image Sampling and Quantization. 4. Image Transforms. 5. Image Representation by Stochastic Models. 6. Image Enhancement. 7. Image Filtering and Restoration. 8. Image Analysis and Computer Vision. 9. Image Reconstruction From Projections. 10. Image Data Compression.

8,504 citations

Journal ArticleDOI
TL;DR: The image coding results, calculated from actual file sizes and images reconstructed by the decoding algorithm, are either comparable to or surpass previous results obtained through much more sophisticated and computationally complex methods.
Abstract: Embedded zerotree wavelet (EZW) coding, introduced by Shapiro (see IEEE Trans. Signal Processing, vol.41, no.12, p.3445, 1993), is a very effective and computationally simple technique for image compression. We offer an alternative explanation of the principles of its operation, so that the reasons for its excellent performance can be better understood. These principles are partial ordering by magnitude with a set partitioning sorting algorithm, ordered bit plane transmission, and exploitation of self-similarity across different scales of an image wavelet transform. Moreover, we present a new and different implementation based on set partitioning in hierarchical trees (SPIHT), which provides even better performance than our previously reported extension of EZW that surpassed the performance of the original EZW. The image coding results, calculated from actual file sizes and images reconstructed by the decoding algorithm, are either comparable to or surpass previous results obtained through much more sophisticated and computationally complex methods. In addition, the new coding and decoding procedures are extremely fast, and they can be made even faster, with only small loss in performance, by omitting entropy coding of the bit stream by the arithmetic code.

5,890 citations

Journal ArticleDOI
TL;DR: Eight constructs decellularized hearts by coronary perfusion with detergents, preserved the underlying extracellular matrix, and produced an acellular, perfusable vascular architecture, competent a cellular valves and intact chamber geometry that could generate pump function in a modified working heart preparation.
Abstract: About 3,000 individuals in the United States are awaiting a donor heart; worldwide, 22 million individuals are living with heart failure. A bioartificial heart is a theoretical alternative to transplantation or mechanical left ventricular support. Generating a bioartificial heart requires engineering of cardiac architecture, appropriate cellular constituents and pump function. We decellularized hearts by coronary perfusion with detergents, preserved the underlying extracellular matrix, and produced an acellular, perfusable vascular architecture, competent acellular valves and intact chamber geometry. To mimic cardiac cell composition, we reseeded these constructs with cardiac or endothelial cells. To establish function, we maintained eight constructs for up to 28 d by coronary perfusion in a bioreactor that simulated cardiac physiology. By day 4, we observed macroscopic contractions. By day 8, under physiological load and electrical stimulation, constructs could generate pump function (equivalent to about 2% of adult or 25% of 16-week fetal heart function) in a modified working heart preparation.

2,454 citations

Journal ArticleDOI
01 Sep 1997
TL;DR: This paper examines automated iris recognition as a biometrically based technology for personal identification and verification from the observation that the human iris provides a particularly interesting structure on which to base a technology for noninvasive biometric assessment.
Abstract: This paper examines automated iris recognition as a biometrically based technology for personal identification and verification. The motivation for this endeavor stems from the observation that the human iris provides a particularly interesting structure on which to base a technology for noninvasive biometric assessment. In particular the biomedical literature suggests that irises are as distinct as fingerprints or patterns of retinal blood vessels. Further, since the iris is an overt body, its appearance is amenable to remote examination with the aid of a machine vision system. The body of this paper details issues in the design and operation of such systems. For the sake of illustration, extant systems are described in some amount of detail.

2,046 citations